Mahdi Niknazar; Saeid Amel Jamehdar; Majid Khadem-Rezaiyan; zahra ataee
Abstract
INTRODUCTION: there is no clear relationship between the threshold cycle of COVID-19 and severity of pulmonary involvement in the CT scan of patients. Methods: 254 patients were included. The number of cycle of threshold virus, was extracted. The severity of pulmonary involvement was categorized based ...
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INTRODUCTION: there is no clear relationship between the threshold cycle of COVID-19 and severity of pulmonary involvement in the CT scan of patients. Methods: 254 patients were included. The number of cycle of threshold virus, was extracted. The severity of pulmonary involvement was categorized based on the percentage of involvement of each lobe Based on CT scan. The relationship between the CT number and the involvement in the CT scan, was measured.Results: 254 patients with COVID-19 such as 158 (62.2%) men and 96 (37.8%) women with a mean age and standard deviation of 17.785 ± 60.99 years. The average threshold cycle (CT Value) is 5.912 ± 19.38 and it’s minimum and maximum are 9 and 36. The percentage of right lung involvement was 29.7±46.7% and the percentage of left lung involvement was 29.8±47.8%. The number of people without conflict is 6 (2.4) %, with mild conflict 39 (15.4) %, moderate 65 (25.6%) and severe 144 (56.7%). The number of people without involvement of the right lobe is 11 (4.3%), score 1, 42 (16.5%), score 2, 75 (29.5%), score 3, 51 (20.1%), involvement Score 4, 75 (29.5%).The number of people without left lobe involvement is 12 (4.7%), score 1, 46 (18.1%), score 2, 71 (28%), score 3, 48 (18.9%), involvement Score 4, 77 (30.3%) .Conclusion: With the increase of lung involvement, the amount of threshold cycle has decreased, which can indicate the inverse relationship of threshold cycle with the severity of disease involvement.
Kobra Salimiyan Rizi; Hadi Farsiani; Saeid Amel Jamehdar; Mahboubeh Mohammadzadeh
Abstract
Elizabethkingia meningoseptica is an emerging nosocomial gram-negative, rod-shaped pathogen in patients with underlying diseases. This bacterium is also considered to be a major pathogen in hospitalized patients. Some of the main risk factors for E. meningosepticum infections include immunosuppression ...
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Elizabethkingia meningoseptica is an emerging nosocomial gram-negative, rod-shaped pathogen in patients with underlying diseases. This bacterium is also considered to be a major pathogen in hospitalized patients. Some of the main risk factors for E. meningosepticum infections include immunosuppression (e.g., end-stage hepatic and renal diseases) and prematurity in neonates. Furthermore, E. meningosepticum could cause pneumonia, endocarditis, and bacteremia in adults. The uncommon resistance pattern of this bacterium, as well as its intrinsic resistance to colistin, makes the treatment of the associated infections challenging unless the susceptibility patterns are available. In this article, we have presented the first case of pulmonary coinfection with multidrug-resistant (MDR) Acinetobacter spp. and E. meningoseptica in Iran. A 20-year-old female patient was admitted to our hospital with tetralogy of fallot as an underlying disease since childhood. The patient underwent cardiac surgery. On the third postoperative day (POD), the patient developed lung infection and left-lung collapse. Antibiotic therapy was initiated for MDR Acinetobacter spp. obtained from her primary culture of tracheal discharges. When fever persisted in the patient, the secondary culture of her tracheal discharges was observed to be positive for E. meningoseptica. In this case report, no clinical correlations were observed between the E. meningoseptica isolated from respiratory secretions and the primary respiratory infection, suggesting that E. meningoseptica is an indicator of severe underlying diseases rather than an actual pathogen.