%0 Journal Article %T Sneddon Syndrome with the Initial Presentation of Intracranial Hemorrhage: A Case Report %J Reviews in Clinical Medicine %I Mashhad University of Medical Sciences %Z 2345-6256 %A Khodamoradi, Zohre %A Poursadeghfard, Maryam %A Shamszadeh, Zahra %D 2017 %\ 12/01/2017 %V 4 %N 4 %P 165-168 %! Sneddon Syndrome with the Initial Presentation of Intracranial Hemorrhage: A Case Report %K Intracranial Hemorrhage %K livedo reticularis %K Sneddon Syndrome %R 10.22038/rcm.2017.8737 %X Sneddon syndrome (SS) is characterized by chronic, progressive arteriopathy, which causes ischemic stroke and skin lesions. It seems that thrombotic or embolic processes in the vessels may be involved in the pathology of this syndrome. Neurological symptoms always occur due to the ischemic events of the cerebrovascular system, and the associated cutaneous manifestations include deep blue skin lesions with irregular margins, known as livedo reticularis and livedo racemosa. Despite the ischemic events, hemorrhagic cerebral accidents are unusual in SS. Our case was apparently a normal woman with negative medical history who, despite the normal ischemic cerebral manifestations, initially presented with intracranial hemorrhage, which progressed to new skin lesions (livedo reticularis) after a few days. In the follow-up, the patient was diagnosed with SS. %U https://rcm.mums.ac.ir/article_8737_66a9ad6fa2a5b2b8e72fc5b5d0735096.pdf