Document Type: Original article
Research Center for Patients Safety, Mashhad University of Medical Sciences, Mashhad, Iran
Department of Pediatrics, Mashhad University of Medical Sciences, Mashhad, Iran
Eye Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Pediatrics Neurology, Faculty of Medicine, Mashhad university of Medical Sciences
Biological sciences student, California state university, East Bay, Hayward, California
Objective: To evaluate mean folic acid serum levels in febrile children with or without seizures.
Methods: The mean folic acid serum levels and demographic data of 100 children aged 6 to 60 months, admitted to the Ghaem Hospital of Mashhad, Iran in 2018-2019, were collected, where the patients with febrile seizure were considered as the case group and the febrile ones without seizure as the control group. The inclusion criteria were children aged 6 to 60 months with febrile seizures who were admitted to the pediatric ward. The exclusion criteria were having a past medical history of seizure, meningitis, or encephalitis.
Results: There were 49 febrile convulsive children (cases) and 51 febrile children without a seizure (controls). The mean serum folic acid level was 7.07 and 9.89 ng/ml for cases and controls respectively (P-value < 0.001).
Conclusion: Children with febrile seizures had significantly lower serum folic acid levels than febrile children without a seizure.