1Lung Disease Research Center, Pulmonary Department of Pulmonary , Mashhad University Of Medical Sciences ,Mashhad ,Iran
2Department of neurology, School of Medicine, Mashhad University Of Medical Sciences ,Mashhad ,Iran
Restless Legs Syndrome (RLS) is a common chronic sensory motor disorder that prevents initiation and/or sleep staying . This syndrome has uncomfortable sensations in their legs (and sometimes arms or other parts of the body), with moving their legs to relieve this sensations . The symptoms of RLS are usually worse in the evening and at night. The diagnosis of RLS is clinical and based primarily on the patient's history International Restless leg Syndrome Group Study (IRLSGS) evaluates symptoms and severity of RLS RLS can be divided in to two groups: primary and secondary. Iron deficiency, Parkinson’s disease, kidney failure, diabetes, peripheral neuropathy, pregnancy may cause RLS Antinausea, antipsychotic drugs, some antidepressants, and antihistamines, may worsen symptoms.RLS was seen in Chronic obstructive pulmonary disease(COPD),which makes it worse outcome. COPD is a main preventable health problem leads to morbidity and mortality. Thus RLS in COPD causes excessive daytime hyper somnolence, fatigue ,poor quality of life ,disability and neuropsychological complications, such as social isolation, frequent daytime headaches, anxiety and depression.