1Professor of Pediatric Neurology, Iranian Child Neurology Center of Excellence, Pediatric Neurology Department, Mofid Children’s Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences (SBMU), Tehran, Iran
2Professor of Pediatric Neurology, Iranian Child Neurology Center of Excellence, Pediatric Neurology Department, Mofid Children&rsquo;s Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences (SBMU), Tehran, Iran
E Epilepsy is one of the most common neurological disorders during childhood. Also, neurological manifestations are the prominent signs and symptoms in inherited neurometabolic disorders. The proper diagnosis of neurometabolic disorder in a patient with epilepsy increases the possibility of a specific treatment, which leads to improve epilepsy .Thus, it is quite necessary to make an effort to diagnose potentially treatable epileptic disorders. We have different types of seizures in neurometabolic disorders, which are often (without treatment of underline neurometabolic disorders) refractory to antiepileptic drugs. Patients with underlying disorders have severe clinical presentations, including refractory seizures, and do not usually respond to antiepileptic drugs. In epileptic patients with developmental delay and/or regression, abnormal neurologic examination, and abnormal brain imaging with some specific patterns, neurometabolic disorders should be considered; some of these disorders are among treatable diseases. Therefore, neurologist should consider the etiology of epilepsy, especially in pediatric patients and the treatment should not be restricted to symptomatic therapy. The present article aimed at introducing some treatable causes of epilepsy in pediatric patients.