Genetic diversity of clinical isolates of Mycobacterium tuberculosis in Northeast of Iran

Samaneh Saedi; kiarash ghazvini; Masoud Youssefi; Hadi Safdar; saman soleimanpour; Parviz Afrough; Amir Azimian; hamid solgi; Masoud Keikha

Volume 11, Issue 1 , March 2024, , Pages 8-12

https://doi.org/10.22038/rcm.2024.77259.1478

Abstract
  AbstractBackground: Mycobacterium tuberculosis is still one of the most dangerous human pathogens. Identification of the relationships between different clinical strains has remained a high priority for epidemiology research. Methods: In this study, we used MLSA (Multilocus sequence analysis) to generate ...  Read More

The overview on current antimicrobial stewardship strategies in tuberculosis

Masoud Keikha

Volume 8, Issue 4 , December 2021, , Pages 191-193

https://doi.org/10.22038/rcm.2022.61942.1382

Abstract
  Tuberculosis (TB) is remains as one of the most public health concern that approximately 9.9 million individuals were fell ill with TB and 1.5 million people died from this disease (1-2). Routinely, local tuberculosis control programs follow the DOTS (directly-observed treatment, short-course) strategy ...  Read More

Evaluation of Interleukin 33 and ST2 Serum Concentration in Active Tuberculosis Patients

Masoud Youssefi; Golsa Teimouri; Farnaz Zahedi Avval; kiarash ghazvini; Masoud Keikha

Volume 8, Issue 3 , September 2021, , Pages 106-110

https://doi.org/10.22038/rcm.2021.59643.1373

Abstract
  The aim of this study was to determine the serum levels of ST2 protein and interleukin-33 in patients affected to tuberculosis and compare them with the control group. In the present study, at first 30 patients affected to TB were randomly selected and 52 healthy individuals, who were matched with respect ...  Read More

A 4-year Study on Antimicrobial Susceptibility Trends of Nosocomial Infections in a Mashhad Referral Hospital, Mashhad, Iran

Mahbobeh Khammar; Sepideh Hassanzadeh; Fatemeh Tara; Malihe Siahsar; Fatemeh Tahmasbi; Masoud Keikha; Kiarash Ghazvini

Volume 8, Issue 2 , June 2021, , Pages 50-55

https://doi.org/10.22038/rcm.2021.57591.1367

Abstract
  Introduction:In the present study, we evaluated the 4-year antimicrobial resistance trends of several nosocomial pathogens during 2018-2021 in a reffereal Mashhad hospital, Mashhad, Iran. Methods:In this study, we reviewed the data of 70,234 clinical isolates were registred Infection Control Data of ...  Read More

High Salt Intake in Helicobacter Pylori Infected Individuals Can Significantly Increase the Risk of Gastric Cancer; a Global Analysis

kiarash Ghazvini; Masoud Keikha

Volume 8, Issue 1 , March 2021, , Pages 41-43

https://doi.org/10.22038/rcm.2021.56727.1363

Abstract
  The odds ratio with 95%CIs was used to evaluated the synergistic effects between high salt intake and H. pylori infection among gastric cancer cases. Heterogeneity was assessed by I2 index and Cochrane Q-test; In addition, the presence of publication bias was measured using Begg’s p-value and Egger’s ...  Read More

IL-33/ST2 Axis as a Well-Known Endogenous Defense Against Tuberculosis

Mohsen karbalaei; Kiarash Ghazvini; Masoud Keikha

Volume 7, Issue 3 , September 2020, , Pages 127-133

https://doi.org/10.22038/rcm.2020.52536.1338

Abstract
  Tuberculosis (TB) infection is caused by an intracellular bacterium, Mycobacterium tuberculosis (Mtb). The disease is among the most important infectious diseases, which has dedicated most cases of morbidity and mortality to itself worldwide. The global report of World Health Organization (WHO) in 2019 ...  Read More

The evaluation of the microbial community of lower respiratory tracts microbiota in tuberculosis patients and healthy individuals using Metagenomics

kiarash ghazvini; Masoud Youssefi; Masoud Keikha

Volume 7, Issue 2 , June 2020, , Pages 83-86

https://doi.org/10.22038/rcm.2020.49481.1323

Abstract
  Introduction: Tuberculosis is remained as global challenge which is considered as the top cause of human death in worldwide. The presence of lower respiratory tracts microflora can modulate immune response and play important role in susceptibility to TB. The aim of study was comparison ...  Read More

The evaluating expression profile of virulence factors in Helicobacter pylori strains by system biology; an example from Colombia

kiarash ghazvini; Masoud Youssefi; Masoud Keikha

Volume 7, Issue 2 , June 2020, , Pages 87-94

https://doi.org/10.22038/rcm.2020.49087.1320

Abstract
  Abstract Helicobacter pylori is one of the most common bacteria in the stomach, colonizing about one-half of the population in the world, while most of them remain asymptomatic throughout their lives and gastric cancer (GC) occurs in only 1-2% of people. It seems that the final outcomes of Helicobacter ...  Read More

Autophagy as one of the most important strategies for the treatment of tuberculosis; Mini-review

Masoud Youssefi; Majid Eslami; Mohsen Karbalaei; Masoud Keikha; Kiarash Ghazvini

Volume 6, Issue 4 , November 2019, , Pages 135-139

https://doi.org/10.22038/rcm.2019.14176

Abstract
  Cancer is defined as uncontrolled cell division, which could spread or invade various tissues. There are more than 200 types of cancer, including breast, skin, lung, colon, and prostate cancer, and lymphoma, the symptoms and indications of which vary depending on the type of tissues. Cancer has several ...  Read More

B cell-mediated Immunity against Tuberculosis Infection: A Mini Review Study

Mohsen Karbalaei; Saman Soleimanpour; Majid Eslami; Bahman Yousefi; Masoud Keikha

Volume 6, Issue 4 , November 2019, , Pages 140-145

https://doi.org/10.22038/rcm.2020.43872.1293

Abstract
  Mycobacterium tuberculosis (Mtb) is considered to be a major public health concern and a successful intracellular pathogen associated with high mortality worldwide. The Bacillus Calmette-Guerin (BCG) vaccine is the only available vaccine for the prevention of tuberculosis (TB) and tubercular meningitis ...  Read More

The Relevance of HTLV-1-associated Myelopathy/Tropical Spastic Paraparesis in Iran: A Review Study

Masoud Keikha; mohsen Karbalaei Zadeh Babaki; Luiz Augusto Marcondes Fonseca; Jorge Casseb

Volume 6, Issue 2 , June 2019, , Pages 60-65

https://doi.org/10.22038/rcm.2019.38759.1266

Abstract
  Human T-cell lymphotropic virus type I (HTLV-I) is a retrovirus, which is the causative agent of adult T-cell leukaemia (ATL) and HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Evidence suggests that the interaction of HTLV-1 with the cellular-immune system plays a key role in the ...  Read More