%0 Journal Article %T A review of the literature on the association between vitamin D status and the risk of preeclampsia %J Reviews in Clinical Medicine %I Mashhad University of Medical Sciences %Z 2345-6256 %A Movahedian, Ameneh %A Ghomian, Nayereh %A Soltani, Samaneh %A Chalakinia, Nushin %D 2015 %\ 01/01/2015 %V 2 %N 1 %P 15-18 %! A review of the literature on the association between vitamin D status and the risk of preeclampsia %K deficiency %K Preeclampsia %K Pregnancy outcomes %K Vitamin D %R 10.17463/RCM.2015.01.004 %X Complications related to pregnancy and childbirth are the leading causes of disability and death among women of reproductive age in developing countries, constituting at least 18% of the global burden of disease in this age-group. Preeclampsia is a serious, pregnancy-specific disorder that affects up to 8% of pregnant women. Preeclampsia may lead to maternal and offspring mortality and it increases the risk of premature birth and fetal growth restriction. Vitamin D is a potent immunomodulatory agent. There is an evidence pointing toward an association between the vitamin D status and preeclampsia risk. The purpose of the present study is to review the available literature investigating the role of serum levels of vitamin D in preeclampsia.The study findings further highlight the possibility that vitamin D deficiency is a strong, independent risk factor for preeclampsia and vitamin D supplementation may be a simple step to reduce the risk of adverse pregnancy outcomes providing lifelong benefits both to the mother and her developing child. %U https://rcm.mums.ac.ir/article_3659_8458875c6f41611b7e7f34b9a5ab58bd.pdf