ORIGINAL_ARTICLE
Effect of Astaxanthin Treatment on the Sperm Quality of the Mice Treated with Nicotine
Introduction: Today, smoking has become a common habit, and researchers have largely been concerned with the adverse health effects of smoking. Some approaches have been proposed to minimize these effects. Nicotine is an alkaloid, which is considered to be a detrimental agent in smokers. The present study aimed to investigate the protective effects of astaxanthin against the adverse effects of nicotine.Methods: In this study, 42 BALB/c male mice were purchased from Mashhad University in Mashhad, Iran and randomly divided into six groups. Group one received one milliliter of normal saline daily, group two received nicotine (1.5 mg/kg), group three was administered with astaxanthin (25 mg/kg), group four also received astaxanthin (50 mg/kg), group five was administered with astaxanthin (25 mg/kg) and nicotine (1.5 mg/kg), and group 6 was administered with astaxanthin (50 mg/kg) and nicotine (1.5 mg/kg). After the experiments, the epididymis was collected, and the motility, viability, and count of the sperms were evaluated.Results: Nicotine at the dose of 1.5 mg/kg decreased the count, viability, and motility of sperm. In contrast, astaxanthin at the doses of 25 and 50 mg/kg was observed to diminish the destructive effects of nicotine.Conclusion: According to the results, astaxanthin is a potent antioxidant for the protection of the reproductive system against nicotine-induced toxicity.
https://rcm.mums.ac.ir/article_12570_d8fadc3248a8c547b6a341b32bfc6372.pdf
2019-03-01
1
5
10.22038/rcm.2019.37708.1252
Astaxanthin
Infertility
Nicotine
Spermogram
Milad
Ashrafizadeh
dvm.milad73@yahoo.com
1
Department of Basic Science, Veterinary Medicine Faculty, Tabriz University, Tabriz, Iran.
AUTHOR
Zahra
Ahmadi
zahra.ahmadi9996@gmail.com
2
Department of Basic Science, Faculty of Veterinary Medicine, Islamic Azad Branch, University of Shushtar, Khuzestan, Iran.
LEAD_AUTHOR
Ahmadi Z, Ashrafizadeh M. Downregulation of Osteocalcin Gene in Chickens Treated with Lead Acetate II. Int Biol Biomed J. 2018;4. http://ibbj.org/article-1-189-en.html.
1
Ashrafizadeh M, Rafiei H, Ahmadi Z. Histological Changes in the Liver and Biochemical Parameters of Chickens Treated with Lead Acetate II. Iran J Toxicol. 2018;12:1-5.
2
Rafiei H, Ahmadi Z, Ashrafizadeh M. Effects of Orally Administered Lead acetate II on Rat Femur Histology, Mineralization Properties and Expression of Osteocalcin Gene. Int Biol Biomed J. 2018;4:149-155.
3
Rafiei H, Ashrafizadeh M. Expression of Collagen Type II and Osteocalcin Genes in Mesenchymal Stem Cells from Rats Treated with Lead acetate II. Iran J Toxicol. 2018;12:35-40.
4
Mosher WD. Fecundity and infertility in the United States. Am J Public Health. 1988;78:181-182.
5
Abdollahzadeh Soreshjani S, Ashrafizadeh M. The Effects of the Exercise on the Testosterone Level, Heat Shock Proteins and Fertility Potential. Rev Clin Med. 2018;5:12-15.
6
Ibrahim SF, Osman K, Das S, et al. A study of the antioxidant effect of alpha lipoic acids on sperm quality. Clinics (Sao Paulo). 2008;63:545-550.
7
Hammond D, Fong GT, Cummings KM, et al. Cigarette yields and human exposure: a comparison of alternative testing regimens. Cancer Epidemiol Biomarkers Prev. 2006;15:1495-1501.
8
Seema P, Swathy SS, Indira M. Protective effect of selenium on nicotine-induced testicular toxicity in rats. Biol Trace Elem Res. 2007;120:212-218.
9
Da Silva FR, Erdtmann B, Dalpiaz T, et al. Effects of dermal exposure to Nicotiana tabacum (Jean Nicot, 1560) leaves in mouse evaluated by multiple methods and tissues. J Agric Food Chem. 2010;58:9868-98674.
10
Aydos K, Güven MC, Can B, et al. Nicotine toxicity to the ultrastructure of the testis in rats. BJU Int. 2001;88:622-626.
11
Kavitharaj NK, Vijayammal PL. Nicotine administration induced changes in the gonadal functions in male rats. Pharmacology. 1999;58:2-7.
12
Chan KC, Mong MC, Yin MC. Antioxidative and anti‐inflammatory neuroprotective effects of astaxanthin and canthaxanthin in nerve growth factor differentiated PC12 cells. J Food Sci. 2009;74:H225-231.
13
Khan SK, Malinski T, Mason RP, et al. Novel astaxanthin prodrug (CDX-085) attenuates thrombosis in a mouse model. Thromb Res. 2010;126:299-305.
14
Yan T, Zhao Y, Zhang X, et al. Astaxanthin inhibits acetaldehyde-induced cytotoxicity in SH-SY5Y cells by modulating Akt/CREB and p38MAPK/ERK signaling pathways. Mar Drugs. 2016 10;14. pii: E56.
15
Nishida Y, Yamashita E, Miki W. Quenching activities of common hydrophilic and lipophilic antioxidants against singlet oxygen using chemiluminescence detection system. Carotenoid Science. 2007;11(6):16-20.
16
Zhou XY, Zhang F, Hu XT, et al. Depression can be prevented by astaxanthin through inhibition of hippocampal inflammation in diabetic mice. Brain Res. 2017;1657:262-268.
17
Kishimoto Y, Yoshida H, Kondo K. Potential anti-atherosclerotic properties of astaxanthin. Mar Drugs. 2016;14. pii: E35.
18
Jiang X, Chen L, Shen L, et al. Trans-astaxanthin attenuates lipopolysaccharide-induced neuroinflammation and depressive-like behavior in mice. Brain Res. 2016;1649:30-37.
19
Wu Q, Zhang XS, Wang HD, et al. Astaxanthin activates nuclear factor erythroid-related factor 2 and the antioxidant responsive element (Nrf2-ARE) pathway in the brain after subarachnoid hemorrhage in rats and attenuates early brain injury. Mar Drugs. 2014;12:6125-6141.
20
Pan L, Zhou Y, Li XF, et al. Preventive treatment of astaxanthin provides neuroprotection through suppression of reactive oxygen species and activation of antioxidant defense pathway after stroke in rats. Brain Res Bull. 2017;130:211-220.
21
Wu J, Hua Y, Keep RF, et al. Oxidative brain injury from extravasated erythrocytes after intracerebral hemorrhage. Brain Res. 2002;25;953:45-52.
22
Fukuzawa K. Singlet oxygen scavenging in phospholipid membranes. Methods Enzymol. 2000;319:101-110.
23
Goto S, Kogure K, Abe K, et al. Efficient radical trapping at the surface and inside the phospholipid membrane is responsible for highly potent antiperoxidative activity of the carotenoid astaxanthin. Biochim Biophys Acta. 2001;1512:251-258.
24
Rafiei H, Ahmadi Z, Ashrafizadeh M. Effects of Orally Administered Lead acetate II on Rat Femur Histology, Mineralization Properties and Expression of Osteocalcin Gene. Int Biol Biomed J. 2018;4:149-155.
25
Razzak AH, Wais SA. The infertile couple: a cohort study in Duhok, Iraq. East Mediterr Health J. 2002;8:234-238.
26
Araoye MO. Epidemiology of infertility: social problems of the infertile couples. West Afr J Med. 2003;22:190-196.
27
Ahmadi Z, Ashrafizadeh M. Down Regulation of Osteocalcin Gene in Chickens Treated with Cadmium. Iran J Toxicol. 2019;13:1-4.
28
Hassanzadeh Davarania F, Ashrafizadeh M, Saberi Riseh R, et al. Antifungal nanoparticles reduce aflatoxin contamination in pistachio. PHJ. 2018;1:25-33.
29
Mohammadinejad R, Dadashzadeh A, Moghassemi S, et al. Shedding light on gene therapy: carbon dots for the minimally invasive image-guided delivery of plasmids and noncoding RNAs. J Adv Res. 2019;18:81-93.
30
Sobhani B, Roomiani S, Ahmadi Z, et al. Histopathological Analysis of Testis: Effects of Astaxanthin Treatment against Nicotine Toxicity. Iran J Toxicol. 2019;13:41-44.
31
Mohammadinejad R, Ahmadi Z, Tavakol S, et al. Berberine as a potential autophagy modulator. J Cell Physiol. 2019 Feb 15. doi: 10.1002/jcp.28325.
32
Abdollahzadeh Soreshjani S, Ashrafizadeh M. Effects of Exercise on Testosterone Level, Heat Shock Protein, and Fertility Potential. Rev Clin Medi. 2018;5:141-145.
33
Saleh RA, Agarwal A, Sharma RK, et al. Effect of cigarette smoking on levels of seminal oxidative stress in infertile men: a prospective study. Fertil Steril. 2002;78:491-499.
34
Gorrod JW. The mammalian metabolism of nicotine: an overview. In: Nicotine and related Alkaloids. Dordrecht:Springer; 1993 p.31-43.
35
Racowsky C, Kaufman ML. Nuclear degeneration and meiotic aberrations observed in human oocytes matured in vitro: analysis by light microscopy. Fertil Steril. 1992;58:750-755.
36
Aitken RJ. Free radicals, lipid peroxidation and sperm function. Reprod Fertil Dev. 1995;7:659-668.
37
Rossato M, Ion Popa F, Ferigo M, et al. Human sperm express cannabinoid receptor Cb1, the activation of which inhibits motility, acrosome reaction, and mitochondrial function. J Clin Endocrinol Metab. 2005;90:984-991.
38
Lagunov A, Anzar M, Sadeu JC, et al. Effect of in utero and lactational nicotine exposure on the male reproductive tract in peripubertal and adult rats. Reprod Toxicol. 2011;31:418-423.
39
Mohammadghasemi F, Jahromi SK. Melatonin ameliorates testicular damages induced by nicotine in mice. Iran J Basic Med Sci. 2018;21:639-644.
40
Carvalho CA, Favaro WJ, Padovani CR, et al. Morphometric and ultrastructure features of the ventral prostate of rats (Rattus norvegicus) submitted to long‐term nicotine treatment. Andrologia. 2006;38:142-151.
41
Gu Y, Xu W, Nie D, et al. Nicotine induces Nme2-mediated apoptosis in mouse testes. Biochem Biophys Res Commun. 2016;472:573-579.
42
Jana K, Samanta PK, De DK. Nicotine diminishes testicular gametogenesis, steroidogenesis, and steroidogenic acute regulatory protein expression in adult albino rats: possible influence on pituitary gonadotropins and alteration of testicular antioxidant status. Toxicol Sci. 2010;116:647-659.
43
Mohammadghasemi F, Jahromi SK, Hajizadeh H, et al. The protective effects of exogenous melatonin on nicotine-induced changes in mouse ovarian follicles. J Reprod Infertil. 2012;13:143-150.
44
Abd El-Aziz GS, El-Fark MO, Hamdy RM. Protective effect of Eruca sativa seed oil against oral nicotine induced testicular damage in rats. Tissue Cell. 2016;48:340-348.
45
Kim KH, Joo KJ, Park HJ, et al. Nicotine induces apoptosis in TM3 mouse Leydig cells. Fertil Steril. 2005;83:1093-1099.
46
Nesseim WH, Haroun HS, Mostafa E, et al. Effect of nicotine on spermatogenesis in adult albino rats. Andrologia. 2011;43:398-404.
47
Nie D, Zhang D, Dai J, et al. Nicotine induced murine spermatozoa apoptosis via up-regulation of deubiquitinated RIP1 by Trim27 promoter hypomethylation. Biol Reprod. 2016;94:31.
48
Oyeyipo IP, Raji Y, Bolarinwa AF. Antioxidant profile changes in reproductive tissues of rats treated with nicotine. J Hum Reprod Sci. 2014;7:41-46.
49
Oyeyipo IP, Raji Y, Bolarinwa AF. Nicotine alters male reproductive hormones in male albino rats: the role of cessation. J Hum Reprod Sci. 2013;6:40-44.
50
Patil SR, Ravindra, Patil SR, et al. Nicotine induced ovarian and uterine changes in albino mice. Indian J Physiol Pharmacol. 1998;42:503-508.
51
Petrik JJ, Gerstein HC, Cesta CE, et al. Effects of rosiglitazone on ovarian function and fertility in animals with reduced fertility following fetal and neonatal exposure to nicotine. Endocrine. 2009;36:281-290.
52
Reddy A, Sood A, Rust PF, et al. The effect of nicotine onin vitro sperm motion characteristics. J Assist Reprod Genet. 1995;12:217-223.
53
Gharagozloo P, Aitken RJ. The role of sperm oxidative stress in male infertility and the significance of oral antioxidant therapy. Hum Reprod. 2011;26:1628-1640.
54
Moazamian R, Polhemus A, Connaughton H, et al. Oxidative stress and human spermatozoa: diagnostic and functional significance of aldehydes generated as a result of lipid peroxidation. Mol Hum Reprod. 2015;21:502-515.
55
de Lamirande E, Leclerc P, Gagnon C. Capacitation as a regulatory event that primes spermatozoa for the acrosome reaction and fertilization. Mol Hum Reprod. 1997;3:175-194.
56
de Lamirande E, Tsai C, Harakat A, et al. Involvement of reactive oxygen species in human sperm arcosome reaction induced by A23187, lysophosphatidylcholine, and biological fluid ultrafiltrates. J Androl. 1998;19:585-594.
57
Lambert H, Overstreet JW, Morales P, et al. Sperm capacitation in the human female reproductive tract. Fertil Steril. 1985;43:325-327.
58
ORIGINAL_ARTICLE
A Comparative Study of Vaginal Misoprostol Moistened with Acetic Acid and Normal Saline in Second-trimester Pregnancy Termination: A Randomized Clinical Trial
Introduction: Second-trimester pregnancy termination with live fetuses is an important issue in obstetric practice since it is more challenging than first- and third-trimester pregnancy termination. The present study aimed to compare the effectiveness of vaginal misoprostol moistened with normal saline and acetic acid in second-trimester pregnancy termination.Methods: This clinical trial was conducted on 95 pregnant women with the gestational age of 14-26 weeks admitted for medical induced abortion. The subjects were randomly divided into two groups. The first group was administered with vaginal misoprostol moistened with acetic acid (n=47), and the second group received vaginal misoprostol moistened with normal saline (n=48). The abortion rate within the first 24 hours, induced abortion interval, length of hospital stay, and curettage and its complications were assessed in the study groups using statistical methods, and the P-value of less than 0.05 was considered significant.Results: Abortion within the first 24 hours occurred in 100% of the patients in the acetic acid group and 75% of the subjects in the normal saline group, and the difference was considered statistically significant (P<0.001). The mean time for fetal delivery was significantly lower in the acetic acid group (12.3±4.8) compared to the normal saline group (17.5±6.6) (P<0.001). In addition, the length of hospital stay was significantly lower in the acetic acid group compared to the normal saline group (P=0.008). The rate of abortion following the second dose of misoprostol was 46.8% in the acetic acid group and 20.8% in the normal saline group. However, no significant differences were observed in curettage and its complications between the groups.Conclusion: According to the results, high vaginal acidity was associated with the increased effectiveness of misoprostol in second-trimester pregnancy termination.
https://rcm.mums.ac.ir/article_12584_c882f0a700269d89fda8b9e196ef898b.pdf
2019-03-01
6
11
10.22038/rcm.2019.38383.1260
Aacetic acid
Induction abortion
Misoprostol
Farideh
Akhlaghi
akhlaghif@mums.ac.ir
1
Obstetrics & Gynecology Department, Medical School, Mashhad University of Medical Sciences, Mashhad, Iran.
LEAD_AUTHOR
Elaham
Rezaie Askarye
rezaeidrel@gmail.com
2
Obstetrics & Gynecology Department, Medical School, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Mona
Najaf Najafi
najafnm@mums.ac.ir
3
Clinical Research Units, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Zohre
Khoee
khoeez1@mums.ac.ir
4
Head Nurse of Obstetric Department, Omalbanin Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
ACOG Practice Bulletin No. 135: Second-trimester abortion. Obstet Gynecol. 2013;121:1394-1406.
1
Jatlaoui TC, Ewing A, Mandel MG, et al. Abortion Surveillance - United States, 2013. MMWR Surveill Summ. 2016;65:1-44.
2
Yilmaz B, Kelekci S, Ertas IE, et al. Misoprostol moistened with acetic acid or saline for second trimester pregnancy termination. Hum Reprod. 2005;20:3067-3071.
3
Cassing H. second trimester pregnancy termination induction medication termination. Available at: www.uptodate.com: Updated in.May 24,2017.
4
Tang OS, Gemzell-Danielsson K, Ho PC. pharmacokinetic profiles, effects on the uterus and side effects. Int J Gynaecol Obstet. 2007;99:S160-167.
5
Najafian A, Rajaei M, Beheshti S. Efficacy of vaginal misoprostol and vaginal washing with 3% acetic acid for first trimester pregnancy termination:A randomized single blind clinical trial. Hormozgan Med J. 2017;20:301-306.
6
Jahed Bozorgan T, Rahmati Jafarabadi N, Zonoubi Z. Comparison of therapeutic and side effects of misoprostol moistened with normal saline and acetic acid in induced abortion. JQUMS. 2014;18:22-27.
7
Zanjani M, Kohpayeh J, Karimi Zh. The Effect of Vaginal pH on the Efficacy of Vaginal Misoprostol for the Induction of Midtrimester Pregnancy Termination. Obstet Gynecol Cancer Res. 2017;2:e8953.
8
Abd-El-Maeboud KH, Ghazy AA, Nadeem AA, et al. Effect of vaginal pH on the efficacy of vaginal misoprostol for induction of midtrimester abortion. J Obstet Gynaecol Res. 2008;34:78-84.
9
Abd-El-Maeboud KH, Ghazy A, Ibrahim A, et al.Vaginal acidity enhancement with a 3% acetic acid gel prior to misoprostol treatment for pregnancy termination in the midtrimester. Int J Gynecol Obstet. 2012;119:248-252.
10
Bhattacharjee N, Saha SP, Ganguly RP, et al. A randomized comparative study on vaginal administration of acetic acid-moistened versus dry misoprostol for mid-trimester pregnancy termination. Arch Gynecol Obstet. 2012;285:311-316.
11
Pongsatha S, Tongsong T. Randomized controlled study comparing misoprostol moistened with normal saline and with acetic acid for second-trimester pregnancy termination.Is it defferent?. J Obstet Gynaecol Res. 2011; 37:882-886.
12
ORIGINAL_ARTICLE
The Beneficial Effects of Curcumin on Cardiovascular Diseases and Their Risk Factors
Curcumin (diferuloylmethane) is a yellow, active substance of an herbal origin, which is mainly derived from turmeric of the ginger family. Extensive research has been focused on the therapeutic effects of this substance on diabetes, cancer, and cardiovascular diseases, and the hepatoprotective properties have attracted the attention of researchers. In addition, curcumin significantly improves oxidative stress, mitochondrial dysfunction, and inflammation. It could also modulate various cell signals in cytokines, chemokines, growth factors, and enzymes. Curcumin attenuates the blood glucose by increasing insulin levels. According to findings, consuming one gram of curcumin per day for one month could decrease total cholesterol, low-density lipoprotein cholesterol, triglyceride, and high-density lipoprotein cholesterol. Moreover, it contributes to the control of some of the main parameters associated with the metabolic syndrome, which is an important risk factor for cardiovascular diseases. Hepatic cholesterol metabolism is also regulated by curcumin, which has a similar function to lovastatin in the long run. Curcumin has been reported to prevent the enlargement of solid tumours. Several have confirmed the therapeutic role of curcumin in the management of the metabolic syndromes and cardiovascular diseases. The present study aimed to review the therapeutic effects of curcumin.
https://rcm.mums.ac.ir/article_12572_c3713672bb553d5b31554becb8e9a29c.pdf
2019-03-01
12
19
10.22038/rcm.2019.33520.1242
Cardiovascular diseases
Curcumin
Diabetes
Asal
Yadollahi
yadollahia931@mums.ac.ir
1
Cardivascolar Department, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Mostafa
dastani
dastanim@mums.ac.ir
2
Cardivascolar Department, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
AUTHOR
Bita
Zargaran
bita.zargaran@hotmail.com
3
Students Research Committee, Faculty of Medicine, Islamic Azad University, Mashhad branch, Mashhad, Iran.
AUTHOR
Amir hossein
Ghasemi
ghasemiah941@mums.ac.ir
4
Student Research Committee, School of Para-Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Hamid reza
Rahimi
rahimihr@mums.ac.ir
5
Neurogenic Inflammation Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
LEAD_AUTHOR
Kunnumakkara AB, Bordoloi D, Padmavathi G , et al. Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases. Br J Pharmacol. 2017;174:1325-1348.
1
Abidi A, Gupta S, Agarwal M, et al. Evaluation of efficacy of curcumin as an add-on therapy in patients of bronchial asthma. J Clin Diagn Res. 2014;8:HC19-24.
2
Ghosh S, Banerjee S, Sil PC . The beneficial role of curcumin on inflammation, diabetes and neurodegenerative disease: A recent update. Food Chem Toxicol. 2015;83:111-124.
3
Prasad S, Gupta SC, Tyagi AK , et al. Curcumin, a component of golden spice: from bedside to bench and back. Biotechnol Adv. 2014;32:1053-1064.
4
Ganjali S, Blesso CN, Banach M, et al. Effects of curcumin on HDL functionality. Pharmacol Res. 2017;119:208-218.
5
Chen FY, Zhou J, Guo N , et al. Curcumin retunes cholesterol transport homeostasis and inflammation response in M1 macrophage to prevent atherosclerosis. Biochem Biophys Res Commun. 2015;467:872-878.
6
Sahebkar A . Curcuminoids for the management of hypertriglyceridaemia. Nat Rev Cardiol. 2014;11:123.
7
Gupta SC, Patchva S, Aggarwal BB. Therapeutic roles of curcumin: lessons learned from clinical trials. AAPS J. 2013;15:195-218.
8
SCHRAUFSTATTER E, BERNT H. Antibacterial action of curcumin and related compounds. Nature. 1949;164:456.
9
Karimian MS, Pirro M, Majeed M. Curcumin as a natural regulator of monocyte chemoattractant protein-1. Cytokine Growth Factor Rev. 2017;33:55-63.
10
Sahebkar A, Cicero AFG, Simental-Mendía LE. Curcumin downregulates human tumor necrosis factor-α levels: a systematic review and meta-analysis ofrandomized controlled trials. Pharmacol Res. 2016;107:234-242.
11
Panahi Y, Rahimnia AR, Sharafi M,et al. Curcuminoid treatment for knee osteoarthritis: a randomized double‐blind placebo‐controlled trial. Phytother Res. 2014;28:1625-1631.
12
Rahmani S, Asgary S, Askari G, et al. Treatment of Non‐alcoholic Fatty Liver Disease with Curcumin: A Randomized Placebo‐controlled Trial. Phytother Res. 2016;30:1540-1548.
13
Khonche A, Biglarian O, Panahi Y, et al. Adjunctive therapy with curcumin for peptic ulcer: a randomized controlled trial. Drug Res (Stuttg). 2016;66:444-448.
14
Rahimi HR, Nedaeinia R, Sepehri Shamloo A, et al. Novel delivery system for natural products: Nano-curcumin formulations. Avicenna J Phytomed. 2016;6:383-398.
15
Mittal N, Joshi R, Hota D, et al . Evaluation of antihyperalgesic effect of curcumin on formalin‐induced orofacial pain in rat. Phytother Res. 2009;23:507-512.
16
Tajik H, Tamaddonfard E, Hamzeh-Gooshchi N. The effect of curcumin (active substance of turmeric) on the acetic acid-induced visceral nociception in rats. Pak J Biol Sci. 2008;11:312-314.
17
Shin SK, Ha TY, McGregor RA, et al. Long‐term curcumin administration protects against atherosclerosis via hepatic regulation of lipoprotein cholesterol metabolism. Mol Nutr Food Res. 2011;55:1829-1840.
18
Anand P, Kunnumakkara AB, Newman RA, et al. Bioavailability of curcumin: problems and promises. Mol Pharm. 2007;4:807-818.
19
Akram M, Shahab-Uddin AA, Usmanghani K, et al. Curcuma longa and curcumin: a review article. Rom J Biol Plant Biol. 2010;55:65-70.
20
Rahimi HR, Jaafari MR, Mohammadpour AH, et al. Curcumin: reintroduced therapeutic agent from traditional medicine for alcoholic liver disease. Asia Pac J Med Toxicol. 2015;4:25-30.
21
Zhao JF, Ching LC, Huang YC, et al. Molecular mechanism of curcumin on the suppression of cholesterol accumulation in macrophage foam cells and atherosclerosis. Mol Nutr Food Res. 2012;56:691-701.
22
Kunjathoor VV, Febbraio M, Podrez EA, et al. Scavenger receptors class AI/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages. J Biol Chem. 2002;277:49982-49988.
23
van Furth R, Cohn ZA. The origin and kinetics of mononuclear phagocytes. J Exp Med. 1968;128:415-435.
24
Sozzani S, Molino M, Locati M, et al. Receptor-activated calcium influx in human monocytes exposed to monocyte chemotactic protein-1 and related cytokines. J Immunol. 1993;150:1544-1553.
25
Zhang ZJ, Zhao LX, Cao DL , et al. Curcumin inhibits LPS-induced CCL2 expression via JNK pathway in C6 rat astrocytoma cells. Cell Mol Neurobiol. 2012;32:1003-1010.
26
Abe Y, Hashimoto S, Horie T. Curcumin inhibition of inflammatory cytokine production by human peripheral blood monocytes and alveolar macrophages. Pharmacol Res. 1999;39:41-47.
27
Jang EM, Choi MS, Jung UJ , et al. Beneficial effects of curcumin on hyperlipidemia and insulin resistance in high-fat–fed hamsters. Metabolism. 2008;57:1576-1583.
28
Sahebkar A. Molecular mechanisms for curcumin benefits against ischemic injury. Fertil Steril. 2010;94:e75-76.
29
Rivera-Mancía S, Lozada-García MC, Pedraza-Chaverri J. Experimental evidence for curcumin and its analogs for management of diabetes mellitus and its associated complications. Eur J Pharmacol. 2015;756:30-37.
30
Aathira R, Jain V. Advances in management of type 1 diabetes mellitus. World J Diabetes. 2014;5:689-696.
31
Ghosh J, Das J, Manna P, et al. Taurine prevents arsenic-induced cardiac oxidative stress and apoptotic damage: Role of NF-κB, p38 and JNK MAPK pathway. Toxicol Appl Pharmacol. 2009;240:73-87.
32
Topcu-Tarladacalisir Y, Akpolat M, Uz YH, et al. Effects of Curcumin on Apoptosis and Oxidoinflammatory Regulation in a Rat Model of Acetic Acid–Induced Colitis: The Roles of c-Jun N-Terminal Kinase and p38 Mitogen-Activated Protein Kinase. J Med Food. 2013;16:296-305.
33
Soliman MM, Nassan MA, Ismail TA. Immunohistochemical and molecular study on the protective effect of curcumin against hepatic toxicity induced by paracetamol in Wistar rats. BMC Complement Altern Med. 2014;14:457.
34
Garufi A, Trisciuoglio D, Porru M, et al. A fluorescent curcumin-based Zn (II)-complex reactivates mutant (R175H and R273H) p53 in cancer cells. J Exp Clin Cancer Res. 2013;32:72.
35
Chougala MB, Bhaskar JJ, Rajan MG, et al. Effect of curcumin and quercetin on lysosomal enzyme activities in streptozotocin-induced diabetic rats. Clin Nutr. 2012;31:749-755.
36
Zhang DW, Fu M, Gao SH, et al. Curcumin and diabetes: a systematic review. Evid Based Complement Alternat Med. 2013;2013:636053.
37
Shoba G, Joy D, Joseph T, et al. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med. 1998;64:353-356.
38
Srinivasan M. Effect of curcumin on blood sugar as seen in a diabetic subject. Indian J Med Sci. 1972;26:269-270.
39
Majmudar MD, Nahrendorf M. Cardiovascular molecular imaging: the road ahead. J Nucl Med. 2012;53:673-676.
40
Li YB, Gao JL, Zhong ZF, et al. Bisdemethoxycurcumin suppresses MCF-7 cells proliferation by inducing ROS accumulation and modulating senescence-related pathways. Pharmacol Rep. 2013;65:700-709.
41
Amato A, Caldara GF, Nuzzo D, et al. NAFLD and Atherosclerosis Are Prevented by a Natural Dietary Supplement Containing Curcumin, Silymarin, Guggul, Chlorogenic Acid and Inulin in Mice Fed a High-Fat Diet. Nutrients. 2017;9. pii: E492.
42
Husain K, Hernandez W, Ansari RA, et al. Inflammation, oxidative stress and renin angiotensin system in atherosclerosis. World J Biol Chem. 2015;6:209-217.
43
Expert Panel on Detection E. Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). JAMA. 2001;285:2486.
44
Fielding CJ, Fielding PE. Molecular physiology of reverse cholesterol transport. J Lipid Res. 1995;36:211-228.
45
Barter PJ, Caulfield M, Eriksson M, et al. Effects of torcetrapib in patients at high risk for coronary events. N Engl J Med. 2007;357:2109-2122.
46
Kleemann R, Zadelaar S, Kooistra T. Cytokines and atherosclerosis: a comprehensive review of studies in mice. Cardiovasc Res. 2008;79:360-376.
47
Li AC, Glass CK. The macrophage foam cell as a target for therapeutic intervention. Nat Med. 2002;8:1235-1242.
48
Kempaiah RK, Srinivasan K. Integrity of erythrocytes of hypercholesterolemic rats during spices treatment. Mol Cell Biochem. 2002;236:155-161.
49
Asai A, Nakagawa K, Miyazawa T. Antioxidative effects of turmeric, rosemary and capsicum extracts on membrane phospholipid peroxidation and liver lipid metabolism in mice. Biosci Biotechnol Biochem. 1999;63:2118-2122.
50
Aggarwal BB. Targeting inflammation-induced obesity and metabolic diseases by curcumin and other nutraceuticals. Annu Rev Nutr. 2010;30:173-199.
51
Ganjali S, Sahebkar A, Mahdipour E, et al. Investigation of the effects of curcumin on serum cytokines in obese individuals: a randomized controlled trial. ScientificWorldJournal. 2014;2014:898361 .
52
Rao DS, Sekhara NC, Satyanarayana MN, et al. Effect of curcumin on serum and liver cholesterol levels in the rat. J Nutr. 1970;100:1307-1315.
53
Chow FY, Nikolic-Paterson DJ, Ozols E, et al. Monocyte chemoattractant protein-1 promotes the development of diabetic renal injury in streptozotocin-treated mice. Kidney Int. 2006;69:73-80.
54
Esmaily H, Sahebkar A, Iranshahi M, et al. An investigation of the effects of curcumin on anxiety and depression in obese individuals: a randomized controlled trial. Chin J Integr Med. 2015;21:332-338 .
55
Srivastava G, Mehta JL. Currying the heart: curcumin and cardioprotection. J Cardiovasc Pharmacol Ther. 2009;14:22-27.
56
Sudano I, Spieker LE, Hermann F, et al. Protection of endothelial function: targets for nutritional and pharmacological interventions. J Cardiovasc Pharmacol. 2006;47 Suppl 2:S136-50.
57
Dastani M, Bigdelu L, Hoseinzadeh M, et al. The effects of curcumin on the prevention of atrial and ventricular arrhythmias and heart failure in patients with unstable angina: A randomized clinical trial. Avicenna J Phytomed. 2019;9:1-9.
58
Spieker LE, Lüscher TF. Protection of endothelial function. Handb Exp Pharmacol. 2005;:619-644.
59
Molavi B, Mehta JL. Oxidative stress in cardiovascular disease: molecular basis of its deleterious effects, its detection, and therapeutic considerations. Curr Opin Cardiol. 2004;19:488-493.
60
Griendling KK, FitzGerald GA. Oxidative stress and cardiovascular injury: Part I: basic mechanisms and in vivo monitoring of ROS. Circulation. 2003;108:1912-1916.
61
Wongcharoen W, Phrommintikul A. The protective role of curcumin in cardiovascular diseases. Int J Cardiol. 2009;133:145-151.
62
Shoskes D, Lapierre C, Cruz-Correa M, et al. Beneficial effects of the bioflavonoids curcumin and quercetin on early function in cadaveric renal transplantation: a randomized placebo controlled trial. Transplantation. 2005;80:1556-1559.
63
Mirzabeigi P, Mohammadpour AH, Salarifar M, et al. The effect of curcumin on some of traditional and non-traditional cardiovascular risk factors: A pilot randomized, double-blind, placebo-controlled trial. Iran J Pharm Res. 2015;14:479-486.
64
Paschos P, Tziomalos K. Nonalcoholic fatty liver disease and the renin-angiotensin system: Implications for treatment. World J Hepatol. 2012;4:327-331.
65
Frantz EDC, Penna-de-Carvalho A, Batista TdM, et al. Comparative Effects of the Renin–Angiotensin System Blockers on Nonalcoholic Fatty Liver Disease and Insulin Resistance in C57Bl/6 Mice. Metab Syndr Relat Disord. 2014;12:191-201.
66
Oppenheimer A. Turmeric (curcumin) in biliary diseases. The Lancet. 1937;229:619-621.
67
Wongcharoen W, Jai-Aue S, Phrommintikul A, et al. Effects of curcuminoids on frequency of acute myocardial infarction after coronary artery bypass grafting. Am J Cardiol. 2012;110:40-44.
68
Alwi I, Santoso T, Suyono S, et al. The effect of curcumin on lipid level in patients with acute coronary syndrome. Acta Med Indones. 2008;40:201-210.
69
Mohammadi A, Sahebkar A, Iranshahi M, et al. Effects of supplementation with curcuminoids on dyslipidemia in obese patients: a randomized crossover trial. Phytother Res. 2013;27:374-379.
70
Yang YS, Su YF, Yang HW, et al. Lipid‐Lowering Effects of Curcumin in Patients with Metabolic Syndrome: A Randomized, Double‐Blind, Placebo‐Controlled Trial. Phytother Res. 2014;28:1770-1777.
71
Usharani P, Mateen AA, Naidu MU, et al. Effect of NCB-02, atorvastatin and placebo on endothelial function, oxidative stress and inflammatory markers in patients with type 2 diabetes mellitus. Drugs R D. 2008;9:243-250.
72
Chuengsamarn S, Rattanamongkolgul S, Phonrat B, et al. Reduction of atherogenic risk in patients with type 2 diabetes by curcuminoid extract: a randomized controlled trial. J Nutr Biochem. 2014;25:144-150.
73
Maithili Karpaga Selvi N, Sridhar MG, Swaminathan RP, et al. Efficacy of turmeric as adjuvant therapy in type 2 diabetic patients. Indian J Clin Biochem. 2015;30:180-186.
74
Rahimi HR, Mohammadpour AH, Dastani M, et al. The effect of nano-curcumin on HbA1c, fasting blood glucose, and lipid profile in diabetic subjects: a randomized clinical trial. Avicenna J Phytomed. 2016;6:567-577.
75
Chuengsamarn S, Rattanamongkolgul S, Luechapudiporn R, et al. Curcumin extract for prevention of type 2 diabetes. Diabetes Care. 2012;35:2121-2127.
76
Amin F, Islam N, Anila N, et al. Clinical efficacy of the co-administration of Turmeric and Black seeds (Kalongi) in metabolic syndrome–A double blind randomized controlled trial–TAK-MetS trial. Complement Ther Med. 2015;23:165-174.
77
Panahi Y, Kianpour P, Mohtashami R, et al. Curcumin lowers serum lipids and uric acid in subjects with nonalcoholic fatty liver disease: a randomized controlled trial. J Cardiovasc Pharmacol. 2016;68:223-229.
78
Panahi Y, Kianpour P, Mohtashami R, et al. Efficacy and safety of phytosomal curcumin in non-alcoholic fatty liver disease: a randomized controlled trial. Drug Res (Stuttg). 2017;67:244-251.
79
ORIGINAL_ARTICLE
Custodial Cardioplegia and Cardiac Preservation during pediatric Cardiac Surgery Procedures: A Narrative Review
Controlled intraoperative cardioplegia is indispensable to pediatric cardiac surgery procedures. Several preservation techniques have been proposed for such purposes, with varying application by different surgeons. The custodiol cardioplegia is a recent approach that is considered to be a safe and effective cardiac protector. This narrative review was conducted via searching in four databases, including PubMed, Scopus, Embase, and ScienceDirect. The studies focused on the efficacy and safety of custodiol cardioplegia reviewed, especially in pediatric cardiac surgeries and relevant procedures. In total, 21 articles were eligible, and the findings highlighted the controversies regarding the use of various cardioplegic solutions and the variability of their application by surgeons. However, data were inadequate regarding the optimal cardioplegic solutions in this regard. Some of the studies performed on adults suggested that custodiol cardioplegia may be equivalent to conventional blood cardioplegia. Most of the reviewed articles showed a consensus on the safety and efficacy of custodiol cardioplegia in adult and pediatric cardiac surgeries. It is believed that custodiol procedures are not only easily delivered, but they are also convenient and less time-consuming and provide long-lasting motion and bloodless fields for the surgeon to perform the operation. Therefore, use of custodiol cardioplegia has been reported to be safe, effective, and cost-efficient compared to conventional cardioplegic solutions. However, different findings have also been denoted in some of the studies in this regard, implying the equal effectiveness of these techniques.
https://rcm.mums.ac.ir/article_12450_1dac66fcf6c8d6af05bc0838d04c2bfb.pdf
2019-03-01
20
23
10.22038/rcm.2019.37875.1254
Cardioplegic solution
Custodiol
pediatric cardiac surgery
Javad
Ramezani
ramezanij@mums.ac.ir
1
Assistant professor, Atherosclerosis Prevention Research Center, Department of Cardiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Hamid
Hoseinikhah
hoseinikhahh@mums.ac.ir
2
Assistant professor, Department of Cardiac Surgery, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Kayhan
Mizani
mizanik921@mums.ac.ir
3
Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Mohamadreza
Akbari
mra786emam@yahoo.com
4
General Physician, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Mahsa
Moallemi
moallemim921@mums.ac.ir
5
Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Maryam
Argi
argif2@mums.ac.ir
6
Nursing and Perfusinist, Department of Cardiac Surgery, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Aliasghar
Moeinipour
moinipoora1@mums.ac.ir
7
Associated professor, Department of Cardiac Surgery, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
LEAD_AUTHOR
ORIGINAL_ARTICLE
Current Status and Future Prospect of Brucella Blood Culture in Iran: A Review of the Recent Findings
The prevalence of brucellosis has increased in recent years in some regions in Iran, particularly in the western, northeastern, and some central areas. Undoubtedly, the main causes of brucellosis are the lack of vaccination coverage in livestock and distribution of dairy products. In addition, attention must be paid to the diagnostic difficulties associated with slow growth specificity and use of inefficient methods, which lead to the delayed diagnosis of the disease. All the available diagnostic procedures are currently used for the diagnosis of brucellosis, including isolation on culture media, serological procedures, and molecular techniques. Among these methods, isolation on culture media has shown the minimum efficiency, especially in blood specimens, which are the most commonly requested specimens in disease diagnosis. The influential factors could be the use of unapproved commercial kits, applying outdated diagnostic procedures, and using unqualified specimens in hospitalized patients. The present study aimed to enhance the current status of the isolation method, especially in the endemic areas for brucellosis. Several parameters were assessed in this regard, including the role of laboratory conditions, sampling quality, type of culture media, and various isolation methods, in order to review the studies aiming to increase the efficiency of this method.
https://rcm.mums.ac.ir/article_12377_ddf50e19c070226af3207581536a79d2.pdf
2019-03-01
24
28
10.22038/rcm.2019.38382.1259
Brucella
Blood Specimens
Diagnosis
Massoud
Hajia
massoudhajia@yahoo.com
1
Department of Molecular Biology, Ministry of Health and Medical Education, Tehran, Iran.
LEAD_AUTHOR
Pakzad R, Pakzad I, Safiri S, et al. Spatiotemporal analysis of brucellosis incidence in Iran from 2011 to 2014 using GIS. Int J Infect Dis. 2018;67:129-136.
1
Esmaeili H. Brucellosis in Islamic republic of Iran. J Med Bacteriol. 2014;3:47-57.
2
Moosazadeh M, Abedi G, Kheradmand M, et al. Seasonal pattern of brucellosis in Iran: A systematic review and meta-analysis. Iran J Health Sci. 2016; 4:62-72.
3
Golshani M, Buozari S. A Review of Brucellosis in Iran: Epidemiology, Risk Factors, Diagnosis, Control, and Prevention. Iran Biomed J. 2017; 21:349-59.
4
Abbasi J, Samarghandi Z, Akbarein HA, et al. Rezaeigolestani M. Evaluation of Incidence Rate and Some of Epidemiological Indices of Human Brucellosis in Qazvin Province, Iran During 2002 To 2009. J Hum Environ Health Promot. 2018; 4: 45-48.
5
Christopher S, Umapathy BL, Ravikumar KL. Brucellosis: review on the recent trends in pathogenicity and laboratory diagnosis. J Lab Physicians. 2010; 2: 55-60.
6
Mirnejad R, Jazi FM, Mostafaei S, et al. Epidemiology of brucellosis in Iran: A comprehensive systematic review and meta-analysis study. Microb Pathog. 2017;109:239-247.
7
Hajia M, Sohrabi A. Molecular diagnostic methods of Brucellosis: a note on pitfalls. Iran J Pathol. 2018; 13:294-295.
8
Wang P, Li H, Xu JL. Misidentification of Brucella spp. from blood culture. Rev Med Microbiol. 2016;27:47–49.
9
Yagupsky P. Detection of brucellae in blood cultures. J Clin Microbiol. 1999; 37:3437–3442.
10
Hajia M, Fallah F, Angoti G, et al. Comparison of methods for diagnosing Brucellosis. Lab Med. 2013; 44:29-33.
11
Kassiri H, Amani H, Lotfi M. Epidemiological, laboratory, diagnostic and public health aspects of human brucellosis in western Iran. Asian Pac J Trop Biomed. 2013; 3:589–594.
12
Hajia M. The Challenges in Diagnosis of Brucellosis Serological Tests and Available Approaches. Iran J Med Microbiol. 2018; 12:1-5.
13
Maham S, Shirvani F, Jahromi MH. Comparison of BACTEC 9120 and conventional blood culture systems for isolation of microorganisms from blood and other sterile body fluids. J Pure Appl Microbiol. 2012;6:2039–2044.
14
Hajia M. The prospect of molecular epidemiology of Brucella species in Iran. Rev Clin Med. 2018; 5:130-132.
15
Nouri HR, Marashi MA, Rahimi MT, et al. Tests in Human Brucellosis. Int J Enteric Pathog. 2014;2:e19422.
16
Buchan BW, Mahlen SD, Relich RF. Sentinel level clinical microbiology laboratory guidelines for suspected agents of bioterrorism and emerging infectious diseases. ASM, Washington; 2013.
17
Chosewood LC, Wilson DE. Biosafety in microbiological and biomedical laboratories, 5th ed. U.S. Department of Health and Human Services, Washington, DC;2010.
18
Centers for Disease Control and Prevention. Laboratory-acquired brucellosis—Indiana and Minnesota, 2006. MMWR Morb Mortal Wkly Rep. 2008;57:39-42.
19
Gerberding JL, Romero JM, Ferraro MJ. Case records of the Massachusetts General Hospital. N Engl J Med. 2008;359:1942-1949.
20
Horvat RT, El Atrouni W, Hammoud K, et al. Ribosomal RNA sequence analysis of Brucella infection misidentified as Ochrobactrum anthropi infection. J Clin Microbiol. 2011; 49:1165–1168.
21
Traxler RM, Lehman MW, Bosserman EA, et al. Literature Review of Laboratory-Acquired Brucellosis. J Clin Microbiol. 2013;51:3055-3062.
22
Sayin-Kutlu S, Kutlu M, Ergonul O, et al. Laboratory-acquired brucellosis in Turkey. J Hosp Infect. 2012 ;80:326-330.
23
Hajia M, Safadel N, Samiee SM, et al. Quality Assurance Program for Molecular Medicine Laboratories. Iran J Pub Health. 2013; 42 Supple1:119-124.
24
Centers for Disease Control and Prevention (CDC). Summary of notifiable diseases: United States, 2009. MMWR Morb Mortal Wkly Rep. 2011;58:1-100.
25
Traxler RM, Lehman MW, Bosserman EA, et al. A Literature Review of Laboratory-Acquired Brucellosis. J Clin Microbiol. 2013;51:3055-3062
26
Avijgan M, Hafizi M, Salemi A, et al. Unusual presentation of brucellosis: Afebrile, culture positive brucellosis and culture positive, seronegative brucellosis. Asian Pac J Trop Med. 2009;2:22-27.
27
Araj GF. Update on laboratory diagnosis of human brucellosis. Int J Antimicrob Agents. 2010;36 Suppl 1:S12-17.
28
Al Dahouk S, Nöckler K. Implications of laboratory diagnosis on brucellosis therapy. Expert Rev Anti Infect Ther. 2011;9:833-845.
29
Hajia M. Blood culture of Brucella, Challenges and Limitations. J Res Med Sci. 2018;23:92.
30
Amirzargar A, Hassibi M, Maleknejad P, et al. Comparison of diagnostic methods in hospitalized patients with brucellosis in Iran. Infect Dis Clin Pract. 2009; 17:239-242.
31
Yagupsky P. Detection of brucellae in blood cultures. J Clin Microbiol. 1999;37:3437-3442
32
Corbel MJ. Brucellosis: an overview. Emerg Infect Dis. 1997;3:213-221.
33
Wang P, Li H, Xu JL. Misidentification of Brucella spp. from blood culture. Rev Med Microbiol. 2016; 27:47–49.
34
Purcell B, David L. Hoover DL, et al. In: Martha K. Lenhart MK, Colonel MC, editors. Medical aspects of biological warfare. Washington, DC: The Office of the Surgeon General US Army Medical Department Center and School Borden Institute publishing; 2007. p.185-198.
35
Hajia M, Masjedian FJ. Looking Again at the Diagnosis of Brucellosis Difficulties in Iran. Iran J Med Microbiol. 2018; 12:68-77.
36
Hosseini Doust R, Ahamdi Z, Ahamdi A, et al. Detection of Brucella abortus by alkB and IS711 based primers. J Res Med Sci. 2007; 12:62-67.
37
Hosseini Doust SR, Ahmadi A, Ahmadi Z, et al. Detection of brucella abortus by PCR assay and comparison with culture assay. J Military Med. 2005; 7:239-44.
38
Hajia M. Uncertainty results of molecular diagnostic methods: Causes and Barriers. J Res Med Sci. 2109: In press
39
Hajia M, Safadel N, Secondary Use of Laboratory data: Potentialities and Limitations. Iran J Pathol. 2019: In press.
40
Mantur BG, Mangalgi SS. Evaluation of conventional Castaneda and lysis centrifugation blood culture techniques for diagnosis of human brucellosis. J Clin Microbiol. 2004;42:4327-4328.
41
Hajia M, Keramat F. Study on the rate of brucellosis relapse and efficiency of different treatment protocols among hospitalized patients. J Mil Med. 2003; 5:195-199.
42
Hajia M, Rahbar M, Keramat F. Epidemiological, clinical, diagnostic and treatment aspects of hospitalized brucellosis patients in Hamadan. Ann Trop Med Public Health. 2009; 2:42-45.
43
Hajia M, Rahbar M. Isolation of Brucella from blood culture of hospitalized brucellosis patients. Iran J Clin Infect Dis. 2006;1:5-10.
44
Peerapur BV, Smitha S. Comparison of whole blood culture and blood clot culture for the diagnosis of enteric fever. JKIMSU. 2013; 2:145–146.
45
Mantur BG, Bidari LH, Akki AS, et al. Diagnostic yield of blood clot culture in the accurate diagnosis of enteric fever and human brucellosis. Clin Lab. 2007;53:57–61.
46
Mangalgi S, Sajjan A. Comparison of Three Blood Culture Techniques in the Diagnosis of Human Brucellosis. J Lab Physicians.2014;6:14-17.
47
Maleknejad P, Peeri-DoGaheh H, AmirZargar AA, et al. Diagnosis of brucellosis by use of BACTEC blood culture and confirmation by PCR. Iran J Vet Med. 2007; 62:83-86.
48
Momen-Heravi M, Erami M, Kosha, H, et al. Diagnosis of brucellosis via BACTEC blood culture system. Journal of Isfahan Medical School. 2015; 32 ; 2234-2240.
49
Raj A, Gautam V, Gupta PK, et al. Rapid detection of Brucella by an automated blood culture system at a tertiary care hospital of north India. Indian J Med Res. 2014;139:776-778.
50
Corbel MJ. Brucellosis: an overview. Emerg Infect Dis. 1997;3:213-221.
51
Seleem MN, Boyle SM, Sriranganathan N. A re- emerging zoonosis. Vet Microbiol. 2010;140:392-398
52
Rabozzi G, Bonizzi L, Crespi E, et al. Emerging zoonoses: the “one health approach”. Saf Health Work. 2012;3:77-83.
53
ORIGINAL_ARTICLE
Surgical Management of Various Types of Maxillary Canine Impaction: A Narrative Review
With the exception of the third molar, maxillary canine impaction is considered to be the most common form of tooth impaction. The position of the permanent maxillary canine at the angle of the mouth is strategically important in preserving the harmony and symmetry of the dental arches. The incidence of maxillary canine impaction in the maxilla is more than twice higher compared to the mandible. Approximately one-thirds of the cases are labially located, and two-thirds are palatally located. Bilateral impaction has been reported in 8% of the patients with canine impaction. The treatment procedure is time-consuming and imposes a significant financial burden on the patient. Impacted maxillary canines could be erupted and guided to an appropriate location in the dental arch with early detection, timely interception, and proper surgical management in order to perform orthodontic treatment. Various surgical and orthodontic techniques could be used to guide impacted canines into the arch. Accurate selection of surgical and orthodontic techniques is essential to the successful alignment of impacted teeth. Management of impacted tooth often requires an interdisciplinary approach. In addition, proper cooperation of the orthodontist, oral surgeon, and periodontist seems crucial in this process. The present study aimed to review the clinical and practical aspects required for the management of maxillary canine impaction based on the location and age of the impaction.
https://rcm.mums.ac.ir/article_12395_f6f09c0fc9534cf27c7ad15ea7a67114.pdf
2019-03-01
29
32
10.22038/rcm.2019.35620.1250
canine
impacted
tooth
unerupted
Arezoo
Jahanbin
jahanbina@mums.ac.ir
1
Dental Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Mostafa
Shahabi
shahabim@mums.ac.ir
2
Dental Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Abdolrasoul
Rangrazi
rangrazir@mums.ac.ir
3
Dental Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Parastoo
Namdar
dds.pnamdar@gmail.com
4
Orthodontic Department, Dental Faculty, Mazandaran University of Medical Sciences, Sari, Iran.
AUTHOR
Farzaneh
Lal Alizadeh
laelaf@mums.ac.ir
5
Dental Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
LEAD_AUTHOR
Bishara SE. Impacted maxillary canines: a review. Am J Orthod Dentofacial Orthop. 1992;101:159-171.
1
Proffit WR, Fields HW, and Sarver DM. Contemporary Orthodontics. 4th ed. Louis: Mosby; 2007.
2
Yavuz MS, Aras MH, Büyükkurt MC, et al. Impacted mandibular canines. J Contemp Dent Pract. 2007;8:78-85.
3
Ericson S, Kurol J. Early treatment of palatally erupting maxillary canines by extraction of the primary canines. Eur J Orthod. 1988;10:283-295.
4
Bedoya MM, Park JH. A Review of the Diagnosis and Management of Impacted Maxillary Canines. J Am Dent Assoc. 2009;140:1485-1493.
5
Mathewsa D, Kokich V. Palatally impacted canines: The case for preorthodontic uncovering and autonomous eruption. Am J Orthod Dentofacial Orthop. 2013;143:450-458.
6
Becker A, Kohavi D, Zilberman Y. Periodontal status following the alignment of palatally impacted canine teeth. Am J Orthod. 1983;84:332-336.
7
Khodavi D, Becker A, Zilberman Y. Surgical exposure, orthodontic movement, and final tooth position as factors in periodontal breakdown of treated palatally impacted canines. Am J Orthod. 1984;85:72-77.
8
Zasciurinskiene E, Bjerklin K, Smaliliene D, et al. Initial vertical and horizontal position of palatally impacted maxillary canine and effect on periodontal status following surgical-orthodontic treatment. Angle Orthod. 2008;78:275-280.
9
Caprioglio A, Vanni A, Bolamperti L. Long-term periodontalresponse to orthodontic treatment of palatally impacted maxillary canines. Eur J Orthod. 2013;35:323-328.
10
Kim Y, Hyun HK, Jang KT. The position of maxillary canine impactions and the influenced factors to adjacent root resorption in the Korean population. Eur J Orthod 2012;34:302-306.
11
Yan B, Sun Z, Fields H. Maxillary canine impaction increases root resorption risk of adjacent teeth: a problem of physical proximity. Am J Orthod Dentofacial Orthop. 2012;142:750-757.
12
Johnston WD. Treatment of palatally impacted canine teeth. Am J Orthod. 1969;56:589-596.
13
Clark D. The management of impacted canines: free physiologic eruption. J Am Dent Assoc. 1971;82:836-840.
14
Ferguson J, Parvizi F. Eruption of palatal canines following surgical exposure: a review of outcomes in a series of consecutively treated cases. Br J Orthod. 1997;24:203-207.
15
Kokich VG. Surgical and orthodontic management of impacted maxillary canines. Am J Orthod Dentofacial Orthop. 2004;126:278-283.
16
Becker A, Chaushu S. Surgical Treatment of Impacted Canines What the Orthodontist Would Like the Surgeon to Know. Oral Maxillofac Surg Clin North Am. 2015;27:449-458.
17
Vanarsdall R, Corn H. Soft-tissue management of labially positioned unerupted teeth. Am J Orthod. 1977;72:53-64.
18
Vermette ME, Kokich VG, Kennedy DB. Uncovering labially impacted teeth: apically positioned flap and closed-eruption techniques. Angle Orthod. 1995;65:23-32.
19
Heaney TG, Atherton JD. Periodontal problems associated with the surgical exposure of unerupted teeth. Br J Orthod. 1976;3:79-84.
20
Crescini A, Clauser C, Giorgetti R, et al. Tunnel traction of infraosseous impacted maxillary canines. A three-year periodontal follow-up. Am J Orthod Dentofacial Orthop. 1994;105:61-72.
21
ORIGINAL_ARTICLE
Acquired Torticollis as the Initial and Only Finding in Nasopharyngeal Carcinoma: A Case Report
Torticollis or involuntarily twisted neck is considered to be a sign rather than a condition. Some of the main causes of torticollis are trauma, medication side-effects, infectious and inflammatory processes, and head and neck tumors.A 26-year-old female patient presented with acute acquired torticollis for four months, and the conditions had complicated due to constitutional symptoms, such as weight loss, sweating, and decreased appetite, eventually leading to trismus. Neck CT-scan showed bilateral lymph node enlargements, soft tissue stranding, right-sided asymmetry of the fossa of Rosenmüller (pharyngeal recess), and a heterogeneous enhancing mass on the nasopharynx roof with left extension and bilateral pressure on the Eustachian tube. The biopsy of the mass indicated the infiltration of atypical epithelial cells with marked nuclear atypia in small solid nests within the lymphoid tissue of the nasopharynx, which corresponded to nasopharyngeal carcinoma. However, the patient had no risk factors for nasopharyngeal carcinoma. This study highlighted the importance of a complete work-up for the underlying tumors in the head and neck in the patients presenting with the only finding of torticollis.
https://rcm.mums.ac.ir/article_12367_8ff39ad149760612a07245ebec433d32.pdf
2019-03-01
33
36
10.22038/rcm.2019.37914.1255
Malignancy
nasopharyngeal neoplasm
Torticollis
Mandana
Khodashahi
mkhodashahi53@gmail.com
1
Rheumatic Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
LEAD_AUTHOR
Zahra
Havashki
havashki.zahra@gmail.com
2
Rheumatic Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Kamran
Khazaeni
khazaenik@mums.ac.ir
3
Otorhinolaryngology Head and Neck Surgery, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Amir Hossein
Jafarian
jafarianah@mums.ac.ir
4
Department of Pathology, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Per H, Canpolat M, Tümtürk A, et al. Different etiologies of acquired torticollis in childhood. Childs Nerv Syst. 2014;30:431-440.
1
Tumturk A, Kaya Ozcora G, et al. Torticollis in children: an alert symptom not to be turned away. Childs Nerv Syst. 2015;31:1461-1470.
2
Tomczak KK, Rosman NP. Torticollis. J Child Neurol. 2013;28:365-378.
3
Soundappan SV, Darwish B, Chaseling R. Traumatic spinal epidural hematoma-unusual cause of torticollis in a child. Pediatr Emerg Care. 2005;21:847-849.
4
Hasegawa J, Tateda M, Hidaka H, et al. Retropharyngeal abscess complicated with torticollis: case report and review of the literature. Tohoku J Exp Med. 2007;213:99-104.
5
Fasano A, Bentivoglio AR, Ialongo T, et al. Treatment with botulinum toxin in a patient with myasthenia gravis and cervical dystonia. Neurology. 2005;64:2155-2156.
6
Kumandaş S, Per H, Gümüş H, et al. Torticollis secondary to posterior fossa and cervical spinal cord tumors: report of five cases and literature review. Neurosurg Rev. 2006;29:333-338.
7
Akhaddar A, Boucetta M. Solitary osteochondroma of the cervical spine presenting as recurrent torticollis. Pan Afr Med J. 2014;17:271.
8
Jemni S, Frioui S. Torticollis revealing medullary tumor in a child. Pan Afr Med J. 2015;21:26.
9
Fąfara-Leś A, Kwiatkowski S, Maryńczak L, et al. Torticollis as a first sign of posterior fossa and cervical spinal cord tumors in children. Childs Nerv Syst. 2014;30:425-430.
10
Sellami M, Kallel S, Masmoudi M, et al. Nasopharyngeal carcinoma presenting as a peritonsillar abscess. Egyptian Journal of Ear, Nose, Throat and Allied Sciences. 2015;16:105-107.
11
Bruce JP, Yip K, Bratman SV, et al. Nasopharyngeal Cancer: Molecular Landscape. J Clin Oncol. 2015;33:3346-3355.
12
Yeoh X, Pua K. An Unusual Presentation of Tuberculosis of the Nasopharynx. J Tuberc Res. 2015;3:50-53.
13
Shen C, Ying H, Lu X, et al. Nasopharyngeal carcinoma with central nervous system metastases: Two case reports and a review of the literature. Medicine (Baltimore) 2017;96(49):e9175.
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ORIGINAL_ARTICLE
Peritonitis Due to Rothia dentocariosa in Iran: A Case Report
Rothia dentocariosa (R. dentocariosa) is a gram-positive bacterium, which is a microorganism that normally resides in the mouth and respiratory tract. R. dentocariosa is known to involve in dental plaques and periodontal diseases. However, it is considered an organism with low pathogenicity and is associated with opportunistic infections. Originally thought not to be pathogenic in humans, R. dentocariosa was first described to cause infections in a 19-year-old female with periappendiceal abscess in 1975. The most prevalent human infections caused by R. dentocariosa include infective endocarditis, bacteremia, endophthalmitis, corneal ulcer, septic arthritis, pneumonia, and peritonitis associated with continuous ambulatory peritoneal dialysis. Three main factors have been reported to increase the risk of the cardiac and extra-cardiac infections caused by R. dentocariosa, including immunocompromised conditions, pre-existing cardiac disorders, and poor oral hygiene. Peritoneal dialysis (PD) may induce peritonitis presumably due to hematogenous spread from gingival or periodontal sources. This case study aimed to describe a former PD patient presenting with peritonitis. Oral hygiene is a basic principle in PD patients for the prevention of peritonitis. It is speculated that our patient might have had an occult oral source of R. dentocariosa.
https://rcm.mums.ac.ir/article_12581_eecd8de8340937562597d61830886f6b.pdf
2019-03-01
37
39
10.22038/rcm.2019.38535.1261
Oral hygiene
Peritoneal dialysis
Rothia dentocariosa
Kobra
Salimiyan Rizi
salimiank951@mums.ac.ir
1
Department of Microbiology and Virology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Hadi
Farsiani
farsianih@mums.ac.ir
2
Antimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
LEAD_AUTHOR
Kiarash
Ghazvini
ghazvink@mums.ac.ir
3
Antimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Masoud
Youssefi
youssefim@mums.ac.ir
4
Antimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Piraino B, Bailie GR, Bernardini J, et al. ISPD guidelines/recommendations. Perit Dial Int. 2005;25:107-131.
1
Li PK, Szeto CC, Piraino B, et al. Peritoneal dialysis-related infections recommendations: 2010 update. Perit Dial Int. 2010;30:393-423.
2
Austin B. Bergey’s Manual of Systematics of Archaea and Bacteria. Wiley :Hoboken, New Jersey ;2015.
3
von Graevenitz A, Pünter-Streit V, Riegel P, et al. Coryneform bacteria in throat cultures of healthy individuals. J Clin Microbiol. 1998;36:2087-2088.
4
Von Graevenitz A. Rothia dentocariosa: taxonomy and differential diagnosis. Clin Microbiol Infect. 2004;10:399-402.
5
Yang CY, Hsueh PR, Lu CY, et al. Rothia dentocariosa bacteremia in children: report of two cases and review of the literature. J Formos Med Assoc. 2007;106:S33-S38.
6
MacKinnon M, Amezaga M, MacKinnon J. A case of Rothia dentocariosa endophthalmitis. Eur J Clin Microbiol Infect Dis. 2001;20:756-757.
7
Kronvall G, Lannér‐Sjöberg M, von Stedingk LV, et al. Whole cell protein and partial 16S rRNA gene sequence analysis suggest the existence of a second Rothia species. Clin Microbiol Infect. 1998;4:255-263.
8
Droz S, Zbinden R, Zbinden R. Rothia dentocariosa. Available at: http://www.antimicrobe.org/b230.asp.
9
Salamon SA, Prag J. Three cases of Rothia dentocariosa bacteraemia: frequency in Denmark and a review. Scand J Infect Dis. 2002;34:153-157.
10
Uchibori S, Tsuzukibashi O, Kobayashi T, Aida M. Localization of the genus Rothia in the oral cavity. International Journal of Oral-Medical Sciences. 2013;11:207-210.
11
Ferraz V, McCarthy K, Smith D, et al. Rothia dentocariosa endocarditis and aortic root abscess. J Infect. 1998;37:292-295.
12
Kong R, Mebazaa A, Heitz B, et al. Case of triple endocarditis caused by Rothia dentocariosa and results of a survey in France. J Clin Microbiol. 1998;36:309-310.
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