TY - JOUR ID - 2325 TI - Sexual differences of human brain JO - Reviews in Clinical Medicine JA - RCM LA - en SN - 2345-6256 AU - Pezeshki Rad, Masoud AU - Momennezhad, Mahdi AU - Naseri, Shahrokh AU - Nahidi, Mahsa AU - Mahmoudzadeh, Abolfazl AU - Aminzadeh, Behzad AD - Department of Radiology, School of medicine, Mashhad University of Medical Sciences, Mashhad, Iran AD - Department of Medical Physics, School of medicine, Mashhad University of Medical Sciences, Mashhad, Iran AD - Department of Psychiatry, School of medicine, Mashhad University of Medical Sciences, Mashhad, Iran Y1 - 2014 PY - 2014 VL - 1 IS - 2 SP - 51 EP - 56 KW - Brain KW - magnetic resonance imaging KW - Sexual differences DO - 10.17463/RCM.2014.02.003 N2 - During the last decades there has been an increasing interest in studying the differences between males and females. These differences extend from behavioral to cognitive to micro- and macro- neuro-anatomical aspects of human biology. There have been many methods to evaluate these differences and explain their determinants. The most studied cause of this dimorphism is the prenatal sex hormones and their organizational effect on brain and behavior. However, there have been new and recent attentions to hormone’s activational influences in puberty and also the effects of genomic imprinting. In this paper, we reviewed the sex differences of brain, the evidences for possible determinants of these differences and also the methods that have been used to discover them. We reviewed the most conspicuous findings with specific attention to macro-anatomical differences based on Magnetic Resonance Imaging (MRI) data. We finally reviewed the findings and the many opportunities for future studies. UR - https://rcm.mums.ac.ir/article_2325.html L1 - https://rcm.mums.ac.ir/article_2325_ae0a2d020781ab232673767d92e4ad92.pdf ER -