TY - JOUR ID - 8737 TI - Sneddon Syndrome with the Initial Presentation of Intracranial Hemorrhage: A Case Report JO - Reviews in Clinical Medicine JA - RCM LA - en SN - 2345-6256 AU - Khodamoradi, Zohre AU - Poursadeghfard, Maryam AU - Shamszadeh, Zahra AD - Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran. AD - Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. Y1 - 2017 PY - 2017 VL - 4 IS - 4 SP - 165 EP - 168 KW - Intracranial Hemorrhage KW - livedo reticularis KW - Sneddon Syndrome DO - 10.22038/rcm.2017.8737 N2 - Sneddon syndrome (SS) is characterized by chronic, progressive arteriopathy, which causes ischemic stroke and skin lesions. It seems that thrombotic or embolic processes in the vessels may be involved in the pathology of this syndrome. Neurological symptoms always occur due to the ischemic events of the cerebrovascular system, and the associated cutaneous manifestations include deep blue skin lesions with irregular margins, known as livedo reticularis and livedo racemosa. Despite the ischemic events, hemorrhagic cerebral accidents are unusual in SS. Our case was apparently a normal woman with negative medical history who, despite the normal ischemic cerebral manifestations, initially presented with intracranial hemorrhage, which progressed to new skin lesions (livedo reticularis) after a few days. In the follow-up, the patient was diagnosed with SS. UR - https://rcm.mums.ac.ir/article_8737.html L1 - https://rcm.mums.ac.ir/article_8737_66a9ad6fa2a5b2b8e72fc5b5d0735096.pdf ER -