<?xml version="1.0" encoding="utf-8"?>
			<journal>
			<title>Reviews in Clinical Medicine</title>
			<title_fa></title_fa>
			<short_title>RCM</short_title>
			<subject>Medical Sciences</subject>
			<web_url>https://rcm.mums.ac.ir/</web_url>
			<journal_hbi_system_id>0</journal_hbi_system_id>
			<journal_hbi_system_user></journal_hbi_system_user>
			<journal_id_issn>2345-6256</journal_id_issn>
			<journal_id_issn_online>2345-6892</journal_id_issn_online>
			<journal_id_pii></journal_id_pii>
			<journal_id_doi></journal_id_doi>
			<journal_id_iranmedex></journal_id_iranmedex>
			<journal_id_magiran></journal_id_magiran>
			<journal_id_sid></journal_id_sid>
			<journal_id_nlai></journal_id_nlai>
			<journal_id_science></journal_id_science>
			<language>en</language>
			<pubdate>
				<type>jalali</type>
				<year></year>
				<month></month>
				<day>1</day>
			</pubdate>
			<pubdate>
				<type>gregorian</type>
				<year></year>
				<month></month>
				<day>1</day>
			</pubdate>
			<volume></volume>
			<number></number>
			<publish_type>online</publish_type>
			<publish_edition>1</publish_edition>
			<article_type>fulltext</article_type>
			<articleset><article>
				<language>en</language>
				<article_id_issn></article_id_issn>
				<article_id_issn_online></article_id_issn_online>
				<article_id_pubmed></article_id_pubmed>
				<article_id_pii></article_id_pii>
				<article_id_doi></article_id_doi>
				<article_id_iranmedex></article_id_iranmedex>
				<article_id_magiran></article_id_magiran>
				<article_id_sid></article_id_sid>
				<title_fa></title_fa>
				<title>A comprehensive review of SARS-CoV-2-associated multisystem inflammatory syndrome in children</title>
				<subject_fa></subject_fa>
				<subject></subject>
				<content_type_fa></content_type_fa>
				<content_type>Review</content_type>
				<abstract_fa><![CDATA[]]></abstract_fa>
				<abstract><![CDATA[The coronavirus disease 2019 (COVID-19) has afflicted individuals of all ages, which has a high rate of morbidity and fatality. Although most children with COVID-19 infection experience minor symptoms, a growing proportion of COVID-19 infections in children are linked to a novel multisystem inflammatory syndrome with Kawasaki disease-like clinical features. Multisystem inflammatory syndrome in children (MIS-C) is a novel hyperinflammatory syndrome that can impact about any organ system. The most frequent symptoms are fever and gastrointestinal disorders, although neurologic and dermatologic manifestations are also well-documented. The clinical symptoms of MIS-C coincide with those of Kawasaki disease, toxic shock syndrome, and shock syndrome, making diagnosis challenging. Elevated inflammatory markers are common in MIS-C patients, and an abnormal echocardiogram or electrocardiogram may be present. Intravenous immunoglobulin, anticoagulation, and corticosteroids should all be considered in the treatment of MIS-C patients. Even those with significant cardiovascular involvement, the majority of patients recover without complications. Echocardiographic follow-up is required as coronary aneurysms have been documented. This narrative review is to review the epidemiology, pathophysiology, clinical presentations, laboratory findings, diagnostic criteria, and treatment options for MIS-C patients in order to increase pediatricians’ knowledge of this novel syndrome.]]></abstract>
				<keyword_fa></keyword_fa>
				<keyword>Pediatrics, MIS-C, COVID-19</keyword>
				<start_page>0</start_page>
				<end_page>0</end_page>
				<web_url>https://rcm.mums.ac.ir/article_21449.html</web_url>
			<author_list><author>
				<first_name>Mojtaba</first_name>
				<middle_name></middle_name>
				<last_name>Yousefi Zoshk</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>dr.yousefi.md@gmail.com</email>
				<code>93088</code>
				<coreauthor>No</coreauthor>
				<affiliation>Department of Pediatrics, Faculty of Medicine, AJA University of Medical Sciences, Tehran, Iran.</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Melika</first_name>
				<middle_name></middle_name>
				<last_name>Zamanian</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>melika_zamanian@yahoo.com</email>
				<code>93089</code>
				<coreauthor>No</coreauthor>
				<affiliation>Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Melika</first_name>
				<middle_name></middle_name>
				<last_name>Farshidianfar</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>melikafar4@gmail.com</email>
				<code>93090</code>
				<coreauthor>No</coreauthor>
				<affiliation>MD, Faculty of Medicine, Islamic Azad University &amp;ndash; Mashhad Branch, Mashhad, Iran.</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Alireza</first_name>
				<middle_name></middle_name>
				<last_name>Masoumi</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>alirezamasoumi713@gmail.com</email>
				<code>93091</code>
				<coreauthor>No</coreauthor>
				<affiliation>MD, Faculty of Medicine, Islamic Azad University &amp;ndash; Mashhad Branch, Mashhad, Iran.</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Mohammad Mobin</first_name>
				<middle_name></middle_name>
				<last_name>Mirimoghaddam</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>mobinmiri@gmail.com</email>
				<code>93092</code>
				<coreauthor>No</coreauthor>
				<affiliation>Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Elahe</first_name>
				<middle_name></middle_name>
				<last_name>Bakhshi</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>elahebakhshi2@gmail.com</email>
				<code>93093</code>
				<coreauthor>No</coreauthor>
				<affiliation>Faculty of Pharmacy, Islamic Azad University &amp;ndash; Damghan Branch, Damghan, Iran.</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Anoush</first_name>
				<middle_name></middle_name>
				<last_name>Azarfar</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>azarfara@mums.ac.ir</email>
				<code>93094</code>
				<coreauthor>Yes</coreauthor>
				<affiliation>Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author></author_list>
				</article>
			</articleset>
			</journal>