<?xml version="1.0" encoding="utf-8"?>
			<journal>
			<title>Reviews in Clinical Medicine</title>
			<title_fa></title_fa>
			<short_title>RCM</short_title>
			<subject>Medical Sciences</subject>
			<web_url>https://rcm.mums.ac.ir/</web_url>
			<journal_hbi_system_id>0</journal_hbi_system_id>
			<journal_hbi_system_user></journal_hbi_system_user>
			<journal_id_issn>2345-6256</journal_id_issn>
			<journal_id_issn_online>2345-6892</journal_id_issn_online>
			<journal_id_pii></journal_id_pii>
			<journal_id_doi></journal_id_doi>
			<journal_id_iranmedex></journal_id_iranmedex>
			<journal_id_magiran></journal_id_magiran>
			<journal_id_sid></journal_id_sid>
			<journal_id_nlai></journal_id_nlai>
			<journal_id_science></journal_id_science>
			<language>en</language>
			<pubdate>
				<type>jalali</type>
				<year>0</year>
				<month>0</month>
				<day>1</day>
			</pubdate>
			<pubdate>
				<type>gregorian</type>
				<year>2026</year>
				<month>9</month>
				<day>1</day>
			</pubdate>
			<volume>13</volume>
			<number>3</number>
			<publish_type>online</publish_type>
			<publish_edition>1</publish_edition>
			<article_type>fulltext</article_type>
			<articleset><article>
				<language>en</language>
				<article_id_issn></article_id_issn>
				<article_id_issn_online></article_id_issn_online>
				<article_id_pubmed></article_id_pubmed>
				<article_id_pii></article_id_pii>
				<article_id_doi></article_id_doi>
				<article_id_iranmedex></article_id_iranmedex>
				<article_id_magiran></article_id_magiran>
				<article_id_sid></article_id_sid>
				<title_fa></title_fa>
				<title>Pioglitazone in Type 2 Diabetes Mellitus: A Comprehensive Review of Mechanisms and Efficacy: In vitro and In vivo Studies</title>
				<subject_fa></subject_fa>
				<subject></subject>
				<content_type_fa></content_type_fa>
				<content_type>Review</content_type>
				<abstract_fa><![CDATA[]]></abstract_fa>
				<abstract><![CDATA[Type 2 diabetes mellitus is a long-lasting metabolic disease featuring mitigated insulin sensitivity, compromised beta-cell performance, and elevated circulating glucose concentrations. By 2030, T2DM is anticipated to rank as the seventh primary cause of death. Pioglitazone is a thiazolidinedione (TZD) class medication used to treat T2DM. It can be used alone or in combination with other glycemic-lowering medications. This study aims to elucidate the mechanisms underlying pioglitazone&#039;s effects and its efficacy in T2DM by means of in vitro and in vivo analyses. Clinical studies have reported pioglitazone&#039;s efficacy in lowering glycated hemoglobin (HbA1c), fasting blood glucose (FBS), and homeostasis model assessment-insulin resistance (HOMA-IR). Pioglitazone functions as an insulin-sensitizing agent and improves blood glucose control by increasing peripheral glucose uptake, lowering hepatic glucose release, and gluconeogenesis. Furthermore, the betterment in insulin secretion and sensitivity by pioglitazone is partly attributable to the anti-inflammatory and antioxidant functions of peroxisome proliferator-activated receptor-gamma (PPAR-γ) and PPAR-α. Also, the pioglitazone contributes to improving lipid profiles, reducing blood pressure, and helps to prevent atherosclerosis and liver diseases that are associated with decreased diabetic complications. However, studies have shown that pioglitazone may activate mechanisms associated with β-cell apoptosis, heart failure, fracture risk, and weight gain. Therefore, physicians should anticipate the possibility of these side effects at high doses.]]></abstract>
				<keyword_fa></keyword_fa>
				<keyword>T2DM, pioglitazone, PPAR-&amp;gamma, , PPAR-&amp;alpha, , FBS, HbA1c</keyword>
				<start_page>137</start_page>
				<end_page>144</end_page>
				<web_url>https://rcm.mums.ac.ir/article_28349.html</web_url>
			<author_list><author>
				<first_name>Ali</first_name>
				<middle_name></middle_name>
				<last_name>Nosrati Andevari</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>nosrati.ali70@gmail.com</email>
				<code>124561</code>
				<coreauthor>Yes</coreauthor>
				<affiliation>Department of Clinical Biochemistry, Afzalipour Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author></author_list>
				</article><article>
				<language>en</language>
				<article_id_issn></article_id_issn>
				<article_id_issn_online></article_id_issn_online>
				<article_id_pubmed></article_id_pubmed>
				<article_id_pii></article_id_pii>
				<article_id_doi></article_id_doi>
				<article_id_iranmedex></article_id_iranmedex>
				<article_id_magiran></article_id_magiran>
				<article_id_sid></article_id_sid>
				<title_fa></title_fa>
				<title>Nursing Interventions in Children with Type 1 Diabetes: A Mini-Review of Implications for Renal Health</title>
				<subject_fa></subject_fa>
				<subject></subject>
				<content_type_fa></content_type_fa>
				<content_type>Review</content_type>
				<abstract_fa><![CDATA[]]></abstract_fa>
				<abstract><![CDATA[Children with type 1 diabetes are at heightened risk of early renal alterations that may progress to diabetic kidney disease if not adequately addressed. Nurses play a pivotal role in mitigating this risk through comprehensive, developmentally appropriate interventions that extend beyond glycemic control. This mini-review synthesizes current evidence on nursing interventions relevant to renal health in children with type 1 diabetes, with a focus on education, monitoring, lifestyle modification, and family-centered care. The reviewed literature highlights that structured diabetes education, promotion of optimal insulin adherence, and reinforcement of healthy dietary and hydration practices contribute to improved metabolic stability and reduced renal stress. Regular nursing-led screening for early markers of renal involvement, including blood pressure abnormalities and microalbuminuria, facilitates timely referral and intervention. In addition, psychosocial support and empowerment of children and their families enhance self-management behaviors that are essential for long-term renal protection. Despite growing recognition of the nurse’s role in preventing diabetes-related renal complications, existing studies remain heterogeneous, and high-quality pediatric-focused evidence is limited. This mini-review underscores the need for integrative, nurse-driven strategies that align metabolic management with early renal preservation and calls for further research to strengthen the evidence base guiding nursing practice in this vulnerable population.]]></abstract>
				<keyword_fa></keyword_fa>
				<keyword>Nursing Interventions, Type 1 diabetes, Child, Renal Health</keyword>
				<start_page>145</start_page>
				<end_page>149</end_page>
				<web_url>https://rcm.mums.ac.ir/article_28282.html</web_url>
			<author_list><author>
				<first_name>Jalal</first_name>
				<middle_name></middle_name>
				<last_name>Nourmohammadi</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>nourmohammadij3@mums.ac.ir</email>
				<code>124330</code>
				<coreauthor>Yes</coreauthor>
				<affiliation>Student Research Committee, Faculty of Nursing and Midwifery, Zahedan University of Medical Sciences, Zahedan, Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author></author_list>
				</article><article>
				<language>en</language>
				<article_id_issn></article_id_issn>
				<article_id_issn_online></article_id_issn_online>
				<article_id_pubmed></article_id_pubmed>
				<article_id_pii></article_id_pii>
				<article_id_doi></article_id_doi>
				<article_id_iranmedex></article_id_iranmedex>
				<article_id_magiran></article_id_magiran>
				<article_id_sid></article_id_sid>
				<title_fa></title_fa>
				<title>Association of hs-CRP and Serum Bilirubin Levels with VTE Phenotype (DVT vs PTE) and Demographics: A Cross-sectional Study</title>
				<subject_fa></subject_fa>
				<subject></subject>
				<content_type_fa></content_type_fa>
				<content_type>Original article</content_type>
				<abstract_fa><![CDATA[]]></abstract_fa>
				<abstract><![CDATA[Background: This study aimed to evaluate the levels of hs-CRP and serum bilirubin in patients diagnosed with VTE and to investigate their association with clinical presentation and demographic factors.Methods: This cross-sectional study consisted of 40 patients admitted to two tertiary care hospitals in Mashhad, Iran, with confirmed VTE (either DVT or PTE) between 2021 and 2022 were evaluated. Laboratory data, including hs-CRP, total bilirubin, and direct bilirubin, were extracted from medical records. Comparative analysis was performed between DVT and PTE groups, as well as across gender and age categories.Results: Among the participants, 25 (62.5%) were female, and the mean age was 61.82 ± 17.12 years. Median hs-CRP levels were 26 mg/L (IQR: 10.27-71.10) in DVT patients and 18 mg/L (IQR: 7-74) in PTE patients, with 80% and 70% of patients in these groups, respectively, exceeding the 10 mg/L clinical threshold for systemic inflammation. Patients with PTE were significantly older than those with DVT (p = 0.03). However, no statistically significant differences were found in hs-CRP or bilirubin levels between DVT and PTE patients, nor between genders.Conclusion: Although hs-CRP levels were elevated among VTE patients, their utility in differentiating between DVT and PTE was limited. Serum bilirubin levels did not significantly vary across subgroups. These findings indicate that elevated hs-CRP is a consistent feature of VTE presentations irrespective of subtype, while neither biomarker reliably differentiates between DVT and PTE. These results are descriptive and hypothesis-generating, and underscore the need for larger controlled prospective studies.]]></abstract>
				<keyword_fa></keyword_fa>
				<keyword>Venous thromboembolism, Pulmonary Embolism, C-reactive protein, bilirubin, Venous thrombosis</keyword>
				<start_page>150</start_page>
				<end_page>155</end_page>
				<web_url>https://rcm.mums.ac.ir/article_28316.html</web_url>
			<author_list><author>
				<first_name>Farnoosh</first_name>
				<middle_name></middle_name>
				<last_name>Ebrahimzadeh</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>ebrahimzadehf@mums.ac.ir</email>
				<code>124456</code>
				<coreauthor>No</coreauthor>
				<affiliation>Associate Professor, Department of Internal Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, lran.</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Hashem</first_name>
				<middle_name></middle_name>
				<last_name>Kazemi</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>hashemkazmi@yahoo.com</email>
				<code>124457</code>
				<coreauthor>No</coreauthor>
				<affiliation>Department of Genetics, Faculty of Basic Sciences, Kazerun Islamic Azad University, kazerun, Iran.</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Fariba</first_name>
				<middle_name></middle_name>
				<last_name>Rezaeetalab</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>rezaitalabf@mums.ac.ir</email>
				<code>124458</code>
				<coreauthor>No</coreauthor>
				<affiliation>Pulmonologist, Lung Diseases Research Center, Mashhad University of Medical Science, Mashhad, Iran.</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Mahnaz</first_name>
				<middle_name></middle_name>
				<last_name>Mozdourian</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>mozdorianmh@mums.ac.ir</email>
				<code>124459</code>
				<coreauthor>Yes</coreauthor>
				<affiliation>Lung Diseases Research Center, Mashhad University of Medical Science, Mashhad, Iran.</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author></author_list>
				</article><article>
				<language>en</language>
				<article_id_issn></article_id_issn>
				<article_id_issn_online></article_id_issn_online>
				<article_id_pubmed></article_id_pubmed>
				<article_id_pii></article_id_pii>
				<article_id_doi></article_id_doi>
				<article_id_iranmedex></article_id_iranmedex>
				<article_id_magiran></article_id_magiran>
				<article_id_sid></article_id_sid>
				<title_fa></title_fa>
				<title>Navigating Crisis Pregnancies in Southeast Iran: A Qualitative Study of Factors Influencing Intentions for Induced Abortion and Subsequent Withdrawal</title>
				<subject_fa></subject_fa>
				<subject></subject>
				<content_type_fa></content_type_fa>
				<content_type>Original article</content_type>
				<abstract_fa><![CDATA[]]></abstract_fa>
				<abstract><![CDATA[Background: Although induced abortion is legally restricted in Iran, unintended pregnancies pose complex reproductive dilemmas. Research has focused mainly on central urban centers, leaving decision-making dynamics in disadvantaged border regions under-researched, particularly among women who consider abortion but ultimately decide against it. This study explored factors influencing abortion intentions and subsequent withdrawal among women attending NAFAS counseling centers in Iranshahr, southeastern Iran.Materials and methods: This qualitative study utilized conventional content analysis. Thirty-one women who experienced an unintended pregnancy, seriously considered abortion, but withdrew to continue the pregnancy were purposively recruited from NAFAS centers affiliated with Iranshahr University of Medical Sciences. Data were collected via in-depth, semi-structured interviews until data saturation was achieved, and analyzed following Graneheim and Lundman’s approach. Trustworthiness was ensured via peer debriefing and member checking.Results: Participants’ mean age was 31.2 years (77.4% had ≥ 3 pregnancies). Five themes drove initial abortion considerations: (1) reproductive burden and physical exhaustion, (2) severe economic vulnerability, (3) fear from prior adverse obstetric experiences, (4) life-stage inappropriateness, and (5) perceived inability to provide adequate care. Conversely, withdrawal from abortion was facilitated by four themes: (a) emerging maternal–fetal attachment, (b) perceived support from NAFAS counseling, spousal and family encouragement, and (d) religious beliefs framed around divine will (Razā) and blessing (Barakah).Conclusion: In southeastern Iran, abortion ambivalence reflects a dynamic tension between acute socioeconomic constraints and protective psychosocial and faith-based buffers. Context-tailored reproductive healthcare integrating poverty alleviation, accessible family planning, and culturally anchored, non-judgmental counseling is essential.]]></abstract>
				<keyword_fa></keyword_fa>
				<keyword>Induced abortion, Unintended pregnancy, Qualitative study, reproductive decision-making, women's experiences, Iran</keyword>
				<start_page>156</start_page>
				<end_page>168</end_page>
				<web_url>https://rcm.mums.ac.ir/article_28350.html</web_url>
			<author_list><author>
				<first_name>Somayeh</first_name>
				<middle_name></middle_name>
				<last_name>Sarhadi</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>sarhadi.somayye@gmail.com</email>
				<code>124563</code>
				<coreauthor>No</coreauthor>
				<affiliation>Deputy of Treatment, Iranshahr University of Medical Sciences, Iranshahr, Iran.|Nafas Institute, Iranshahr University of Medical Sciences, Iranshahr, Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Zahra</first_name>
				<middle_name></middle_name>
				<last_name>Ebrahimi Rigi Tanha</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>rigi@irshums.ac.ir</email>
				<code>124564</code>
				<coreauthor>No</coreauthor>
				<affiliation>Department of Nursing, School of Medicine, Iranhahr University of Medical Sciences, Iranshahr, Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Masoud</first_name>
				<middle_name></middle_name>
				<last_name>Keikha</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>masoud.keykha90@gmail.com</email>
				<code>124565</code>
				<coreauthor>Yes</coreauthor>
				<affiliation>Tropical and Communicable Diseases Research Center, Iranshahr University of Medical Sciences, Iranshahr, Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author></author_list>
				</article><article>
				<language>en</language>
				<article_id_issn></article_id_issn>
				<article_id_issn_online></article_id_issn_online>
				<article_id_pubmed></article_id_pubmed>
				<article_id_pii></article_id_pii>
				<article_id_doi></article_id_doi>
				<article_id_iranmedex></article_id_iranmedex>
				<article_id_magiran></article_id_magiran>
				<article_id_sid></article_id_sid>
				<title_fa></title_fa>
				<title>Corneal Aberrations and Topography Changes after Myopic Photorefractive Keratectomy Using Advanced Corneal Explorer and Pentacam</title>
				<subject_fa></subject_fa>
				<subject></subject>
				<content_type_fa></content_type_fa>
				<content_type>Original article</content_type>
				<abstract_fa><![CDATA[]]></abstract_fa>
				<abstract><![CDATA[IIntroduction: This study aimed to evaluate postoperative changes in corneal topography and corneal aberration parameters following photorefractive keratectomy (PRK) as detected by the Advanced Corneal Explorer (ACE) and Pentacam.Methods: In this prospective study, 42 eyes of 42 myopic patients undergoing PRK were examined preoperatively and 4 months postoperatively. Corneal aberration and corneal topography were assessed using two imaging systems based on different measurement principles: the Scheimpflug-based Pentacam (Oculus Optikgeräte GmbH, Wetzlar, Germany) and the swept-source optical coherence tomography (SS-OCT)-based ACE (Technolas Perfect Vision GmbH, Munchen, Germany). Paired t-test was used to evaluate postoperative changes detected by each device.Results: A statistically significant decrease was detected in the mean anterior keratometric values 4 months after PRK via Pentacam and ACE (P&lt;0.05). The mean posterior keratometry significantly increased after surgery using ACE (P&lt;0.001) but no changes were noticed with Pentacam (P&gt;0.20). Four months after PRK, ACE showed a significant change in defocus, horizontal astigmatism as well as in the root mean square (RMS) of higher-order aberrations (all P&lt;0.05). Pentacam showed significant postoperative changes in spherical aberration, vertical tilt, horizontal astigmatism, low order aberration (LOA), HOAs, and fourth-order RMS (P&lt;0.001).Conclusion: Based on the results, both ACE and Pentacam independently detected significant anterior corneal flattening and an increase in certain corneal aberrations following myopic PRK.]]></abstract>
				<keyword_fa></keyword_fa>
				<keyword>Corneal aberration, Photorefractive Keratectomy, Topography</keyword>
				<start_page>169</start_page>
				<end_page>175</end_page>
				<web_url>https://rcm.mums.ac.ir/article_28315.html</web_url>
			<author_list><author>
				<first_name>Mohammad</first_name>
				<middle_name>Hosein</middle_name>
				<last_name>Validad</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>mhovalidad@gmail.com</email>
				<code>124450</code>
				<coreauthor>No</coreauthor>
				<affiliation>Department of Ophthalmology, Al-Zahra Eye Hospital, Zahedan University of Medical Sciences, Zahedan, Iran.</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Tahereh</first_name>
				<middle_name></middle_name>
				<last_name>Rakhshandadi</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>t.rakhshandadi@yahoo.com</email>
				<code>124451</code>
				<coreauthor>No</coreauthor>
				<affiliation>Rehabilitation Sciences Research Center, Department of Optometry, School of Rehabilitation Sciences, Zahedan University of Medical Sciences, Zahedan, Iran.</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Monireh</first_name>
				<middle_name></middle_name>
				<last_name>Mahjoob</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>mahjoob_opt@yahoo.com</email>
				<code>124452</code>
				<coreauthor>No</coreauthor>
				<affiliation>Health Promotion Research Center/Department of Optometry, School of Rehabilitation Sciences, Zahedan University of Medical Sciences, Zahedan, Iran.</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Javad</first_name>
				<middle_name></middle_name>
				<last_name>Heravian Shandiz</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>heraviansj@mums.ac.ir</email>
				<code>124453</code>
				<coreauthor>No</coreauthor>
				<affiliation>Refractive Errors Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Abbas</first_name>
				<middle_name>Ali</middle_name>
				<last_name>Yekta</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>yektaa@mums.ac.ir</email>
				<code>124454</code>
				<coreauthor>No</coreauthor>
				<affiliation>Department of Optometry, Mashhad University of Medical Sciences, Mashhad, Iran.</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Hadi</first_name>
				<middle_name></middle_name>
				<last_name>Ostadi-Moghaddam</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>optometry.h@gmail.com</email>
				<code>124455</code>
				<coreauthor>Yes</coreauthor>
				<affiliation>Refractive Errors Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author></author_list>
				</article><article>
				<language>en</language>
				<article_id_issn></article_id_issn>
				<article_id_issn_online></article_id_issn_online>
				<article_id_pubmed></article_id_pubmed>
				<article_id_pii></article_id_pii>
				<article_id_doi></article_id_doi>
				<article_id_iranmedex></article_id_iranmedex>
				<article_id_magiran></article_id_magiran>
				<article_id_sid></article_id_sid>
				<title_fa></title_fa>
				<title>Effects of Surgical and Non-Surgical Hamstring Lengthening on Hip and Knee Parameters in Children with Cerebral Palsy</title>
				<subject_fa></subject_fa>
				<subject></subject>
				<content_type_fa></content_type_fa>
				<content_type>Original article</content_type>
				<abstract_fa><![CDATA[]]></abstract_fa>
				<abstract><![CDATA[Background: This study aims to investigate changes in femoral head anteversion, popliteal angle, and the effect of internal hamstring lengthening on hip rotation in children with CP undergoing surgical and non-surgical interventions.Methods: This retrospective cross-sectional study included 30 children aged 5-12 years with CP and knee contracture. Patients were divided into two groups: 15 with severe contracture and popliteal angle &gt;70° underwent surgery, and 15 with moderate contracture and popliteal angle 30-70° received non-surgical treatment (botulinum toxin injection). Results: In the surgical group, internal hip rotation decreased by 15°, popliteal angle by 48°, knee extension by 13°, and femoral head anteversion by 10°, while external hip rotation increased by 18°. In the non-surgical group, internal hip rotation decreased by 10°, popliteal angle by 19°, knee extension by 8°, and femoral head anteversion by 19°, while external hip rotation increased by 10° (All p-values=0.001)Conclusions: Internal hamstring lengthening, both surgical and non-surgical (botulinum toxin injection), improves movement (hip rotation and gait pattern) in children with CP, both surgical and non-surgical medial hamstring lengthening yield significant within-group improvements in hip rotation dynamics, popliteal angles, and knee extension deficits within their respective severity cohorts. Rather than comparing superiority, clinical decision-making should be guided by baseline contracture severity, with surgery reserved for severe structural contractures and botulinum toxin type A utilized for moderate spasticity for children with CP.]]></abstract>
				<keyword_fa></keyword_fa>
				<keyword>femoral head anteversion, Popliteal Angle, internal hamstring lengthening, Cerebral palsy</keyword>
				<start_page>176</start_page>
				<end_page>180</end_page>
				<web_url>https://rcm.mums.ac.ir/article_28314.html</web_url>
			<author_list><author>
				<first_name>Farshad</first_name>
				<middle_name></middle_name>
				<last_name>Zandrahimi</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>farshad_z1984@yahoo.com</email>
				<code>124446</code>
				<coreauthor>No</coreauthor>
				<affiliation>Assistant Professor of Orthopaedics, Department of Orthopedics, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Morteza</first_name>
				<middle_name></middle_name>
				<last_name>Hashemian</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>mortezahashemian@kmu.ac.ir</email>
				<code>124447</code>
				<coreauthor>No</coreauthor>
				<affiliation>Department of Anesthesiology, Kerman University of Medical Sciences, Kerman, Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Ali</first_name>
				<middle_name></middle_name>
				<last_name>Madadi Mahani</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>madadimahaniali@gmail.com</email>
				<code>124448</code>
				<coreauthor>No</coreauthor>
				<affiliation>Student Research Committee, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Shahab</first_name>
				<middle_name></middle_name>
				<last_name>Ilka</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>drshahabilka@gmail.com</email>
				<code>124449</code>
				<coreauthor>Yes</coreauthor>
				<affiliation>Assistant Professor of Orthopaedics, Department of Orthopedics, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author></author_list>
				</article><article>
				<language>en</language>
				<article_id_issn></article_id_issn>
				<article_id_issn_online></article_id_issn_online>
				<article_id_pubmed></article_id_pubmed>
				<article_id_pii></article_id_pii>
				<article_id_doi></article_id_doi>
				<article_id_iranmedex></article_id_iranmedex>
				<article_id_magiran></article_id_magiran>
				<article_id_sid></article_id_sid>
				<title_fa></title_fa>
				<title>Effect of Moringa oleifera supplementation on metabolic syndrome risk factors; a review study</title>
				<subject_fa></subject_fa>
				<subject></subject>
				<content_type_fa></content_type_fa>
				<content_type>Review</content_type>
				<abstract_fa><![CDATA[]]></abstract_fa>
				<abstract><![CDATA[Metabolic syndrome is a global health concern associated with an increased risk of cardiovascular diseases and type 2 diabetes. Moringa oleifera, a widely studied medicinal plant, has shown potential in improving metabolic syndrome risk factors. This review article critically evaluates current research on the effects of Moringa oleifera supplementation on metabolic syndrome risk factors in both human and animal studies. Although direct human studies examining the effect of Moringa oleifera on metabolic syndrome are limited, in-depth investigations into individual components of the syndrome provide valuable insights. Human studies exploring the impact of Moringa oleifera on specific risk factors, such as blood pressure and glycemic control, have shown promising outcomes. However, the results are not without contradictions, necessitating further investigation. Animal studies, on the other hand, have provided a wealth of evidence supporting the potential benefits of Moringa oleifera in reducing fasting glucose levels, improving lipid profiles, and combatting obesity. Mechanisms of action include antioxidant properties, enzyme modulation, and gut microbiota regulation. Although human evidence remains limited, Moringa oleifera holds promise as a natural remedy for addressing metabolic syndrome. Further research is required to establish optimal dosages and long-term effects.]]></abstract>
				<keyword_fa></keyword_fa>
				<keyword>Moringa oleifera, metabolic syndrome, Obesity, Hypertension</keyword>
				<start_page>181</start_page>
				<end_page>192</end_page>
				<web_url>https://rcm.mums.ac.ir/article_28485.html</web_url>
			<author_list><author>
				<first_name>Nazanin</first_name>
				<middle_name></middle_name>
				<last_name>Toosi Tali</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>tousinazanin00@gmail.com</email>
				<code>125160</code>
				<coreauthor>No</coreauthor>
				<affiliation>Student Research Committee, Gonabad University of Medical Sciences, Gonabad, Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Salma</first_name>
				<middle_name></middle_name>
				<last_name>Yar</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>salmayar958@gmail.com</email>
				<code>125161</code>
				<coreauthor>No</coreauthor>
				<affiliation>Student Research Committee, Gonabad University of Medical Sciences, Gonabad, Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Saba</first_name>
				<middle_name></middle_name>
				<last_name>Belyani</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>sb.belyani@gmail.com</email>
				<code>125162</code>
				<coreauthor>No</coreauthor>
				<affiliation>Student Research Committee, Gonabad University of Medical Sciences, Gonabad, Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Mohammad</first_name>
				<middle_name></middle_name>
				<last_name>Rashidmayvan</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>rashidmayvan@gmail.com</email>
				<code>125163</code>
				<coreauthor>No</coreauthor>
				<affiliation>Department of Nutrition, Food Sciences and Clinical Biochemistry, School of Medicine, Social Determinants of Health Research Center, Gonabad University of Medical Sciences, Gonabad, Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Elyas</first_name>
				<middle_name></middle_name>
				<last_name>Nattagh-Eshtivani</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>nattagh.elyas@gmail.com</email>
				<code>125159</code>
				<coreauthor>Yes</coreauthor>
				<affiliation>Department of Nutrition, Food Sciences and Clinical Biochemistry, School of Medicine, Social Determinants of Health Research Center, Gonabad University of Medical Sciences, Gonabad, Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author></author_list>
				</article>
			</articleset>
			</journal>