Document Type : Systematic review
Department Of Neurosurgery.Ghaem Hospital.Mashhad.Iran
Introduction: Thalamic tumors can occur in all aging groups, however the children and adolescents are reported as the high risk aging groups. In this systematic review we aimed to investigate the prognosis of thalamic tumors with various histology and different aging groups.
Methods: PubMed was searched for English language articles that studied the prognosis of patients with thalamic lesions regarding the survival and mortality of patients. Inclusion criteria were all the cohort and retrospective studies that included only patients with thalamus tumors. Articles that studied involvement of other parts despite the thalamus or those that included patients with secondary thalamus tumors were excluded.
Results: totally 15 articles were included in this systematic review. The prognosis value of tumor histology, extend of resection, and patients’ age is extracted from the included articles. Results are presented as survival duration and overall survival rate of patients.
Discussion: Although thalamic tumors are difficult to be operated, it is possible to be resected without mortality and morbidity. Factors including histological type of tumor, extent of resection, and presenting age can affect the prognosis of the thalamic tumors.
Conclusion: The prognosis of thalamus tumors is mainly related to tumor type. Benign thalamic tumors have shown favorable outcome regarding the survival duration.