Nasrin moazzen; sepideh bagheri; Nosrat Ghaemi; Sara Nikpour; Mojtaba Lotfi; Hamid Ahanchian
Abstract
Abstract: Background: type 1 diabetes is one of the most chronic diseases of childhood. The therapeutic recommendation for this condition is quite complex and needs changes in lifestyle. Recently the role of gut microbiota has received attention as a possible mechanism in the pathogenesis and control ...
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Abstract: Background: type 1 diabetes is one of the most chronic diseases of childhood. The therapeutic recommendation for this condition is quite complex and needs changes in lifestyle. Recently the role of gut microbiota has received attention as a possible mechanism in the pathogenesis and control of the disease.Methods: One hundred thirty Children aged 6-18 years old with newly diagnosed diabetes type one participate in the trial. They are randomly assigned to the intervention or control group. The patients will receive a six month course of probiotics or placebo besides their conventional treatment with insulin and they will be followed for at least one year. Participants are followed at 3 month intervals for one year. At each visit anthropometrical data, glycemic control and total dose of insulin required to keep the optimal glycemic control is evaluated and registered.Discussion: There is evidence that alterations in gut microbiota is seen in children with diabetes. In this study we aim to evaluate the effect of probiotic administration on the duration of honeymoon period in pediatrics with type one diabetes and their glycemic control and insulin requirements.
Seyed Javad Sayedi; Hanieh Zandi; Sepideh Bagheri
Abstract
Hydatid disease is an important health problem in endemic areas like Iran. Unlike adults, the occurrence of pulmonary hydatid cyst is greater than hepatic cysts in pediatric population. In this study we evaluated the characteristics of pediatric pulmonary hydatid cyst in our region. We reviewed ...
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Hydatid disease is an important health problem in endemic areas like Iran. Unlike adults, the occurrence of pulmonary hydatid cyst is greater than hepatic cysts in pediatric population. In this study we evaluated the characteristics of pediatric pulmonary hydatid cyst in our region. We reviewed the medical records of all children with the diagnosis of pulmonary hydatid cyst in Dr Sheikh’s children hospital between 2015-2019. 30 patients were enrolled during the study period. Diagnosis was confirmed using imaging and serology tests.Mean age of patients was 8.5±2.1 years (range:6-14 years). 73% were male and 80% were living in rural areas. All patients were symptomatic at presentation and the most frequent symptom was cough (76%) followed by dyspnea (43%). The most frequent site of involvement was the lower lobe of the right lung (30% of patients) and bilateral involvement was seen in 16.7% of patients. 13.3% of patients had simultaneous hepatic involvement. Complications were reported as follows: pleural effusion 30%, superinfection and abscess formation 16.7% and pneumothorax in one patient. All patients underwent surgical treatment. Lobectomy was performed in 5 cases (16.6%). Pulmonary hydatid cyst must be considered in children with respiratory symptoms in endemic areas. Early diagnosis might lower the risk of complications and lobectomies.