Effects of Statins on Gut Microbiota (Microbiome)

Milad Ashrafizadeh; Zahra Ahmadi

Volume 6, Issue 2 , June 2019, , Pages 55-59


  Statins are the inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A, which are extensively used to decrease the concentration of cholesterol in patients with hyperlipidemia. Statins are divided into two categories based on their own unique properties. Considering the pleiotropic effects of statins, they ...  Read More

The Targeting of Autophagy and Endoplasmic Reticulum Stress Mechanisms by Honokiol Therapy

Zahra Ahmadi; Sahar Roomiani; Niloofar Bemani; Milad Ashrafizadeh

Volume 6, Issue 2 , June 2019, , Pages 66-73


  In recent decades, special attention has been paid to cell death mechanisms, with the exception of apoptosis. This could be due to the resistance of cells, particularly cancer cells, to apoptosis. Among novel pathways, autophagy and endoplasmic reticulum (ER) stress have attracted the attention of researchers. ...  Read More

Effect of Astaxanthin Treatment on the Sperm Quality of the Mice Treated with Nicotine

Milad Ashrafizadeh; Zahra Ahmadi

Volume 6, Issue 1 , March 2019, , Pages 1-5


  Introduction: Today, smoking has become a common habit, and researchers have largely been concerned with the adverse health effects of smoking. Some approaches have been proposed to minimize these effects. Nicotine is an alkaloid, which is considered to be a detrimental agent in smokers. The present ...  Read More