Samaneh Kouzegaran; Hamid Ahanchian; Seyed Ahmad Emami; Neda Ansari; Jamshid Yousefi; Nasrin Moazzen; Nafiseh Pourbadakhshan; Rana Tafrishi; Aida Ansari; Nasrinsadat Motevalli
Abstract
Introduction: Asthma is a very common chronic disease among children. As for its treatment, in recent years there is an increased tendency towards supplemental treatments. Hence, many of these patients are administered complementary and alternative treatments including herbal medicine.Methods:Through ...
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Introduction: Asthma is a very common chronic disease among children. As for its treatment, in recent years there is an increased tendency towards supplemental treatments. Hence, many of these patients are administered complementary and alternative treatments including herbal medicine.Methods:Through a cross-sectional study, we evaluated the common herbal remedies used in asthmatic children referred to the allergy clinic of Sarvar Children’s Hospital in Mashhad. All data related to the patients (i.e., age, sex, and history of all remedies consumed as well as the responsible persons prescribing the pertinent medications) were recorded in a checklist.Results: In this study, 582 asthmatic children with the average age of 77.4±41.7 months were evaluated. The overall herbal remedies usage was 59.8%. There was no significant differences between age groups, sex, or asthma severity and herbal remedy usage. Thirty-seven different herbal remedies were prescribed to the patients, the most common herb was thymes (65.3%) followed by a four-seed herbal mixture (23.6%), Plantago major (12%) and Cydonia oblonga (quince) (10.8%).Conclusion:Limited information is available regarding complementary and alternative medicine in asthmatic children in Iran. The present study showed the high prevalence of herbal medicine usage in asthmatic children in this region. Hence, further studies should determine the clinical benefits of these remedies
Azadeh Zare Feizabadi; Abdolreza Malek; Hamid Ahanchian
Abstract
The B lymphocyte developmental blocks agammaglobulinemia, leading to peripheral B cell depletion and plasma immunoglobulin reduction. Agammaglobulinemia is a rare yet severe disease since it is presented with recurrent sinopulmonary and skin, central nervous system, bone, and joint infections. The onset ...
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The B lymphocyte developmental blocks agammaglobulinemia, leading to peripheral B cell depletion and plasma immunoglobulin reduction. Agammaglobulinemia is a rare yet severe disease since it is presented with recurrent sinopulmonary and skin, central nervous system, bone, and joint infections. The onset of the disease is reported to be at the age of six months. Associations have been reported between arthritis and immunodeficiency disorders, such as agammaglobulinemia and common variable immunodeficiency (CVID). This study aimed to present the case of a 3.5-year-old female with a three-month history of the swelling of the left knee, mimicking oligoarticular juvenile idiopathic arthritis. After the initiation of immunosuppressive treatment, the patient developed large, tender, erythematous lesions on the inguinal region bilaterally, which developed to ecthyma gangrenosum due to Pseudomonas. The patient’s mother also reported recurrent episodes of infections since the patient was a one-year-old infant. Subsequent to the immunological examinations and laboratory tests, the patient was diagnosed with autosomal recessive agammaglobulinemia due to low serum immunoglobulin concentration and the absence of peripheral B cells. Primary immunodeficiency conditions (particularly agammaglobulinemia) and CVID should be considered in children with arthritis and recurrent infections. Moreover, immunological analysis should be performed prior to treatment in these children