Hesaneh Izadyar; Mitra Ahadi; Ahmad Khosravi Khorashad; Hassan Saadatnia; Hasan Vosoghinia; Mohamadreza Farzanehfar; Ali Beheshti Namdar; Elham Mokhtari Amirmajdi; Sahar Khorasani; Hamid Reza Akbari; Foad Faroughi Bojd
Abstract
Introduction: The present study was conducted to evaluate the prevalence of trend and use of complementary and alternative medicine in patients referring to the Gastroenterology clinics in Mashhad. Methods: The present cross-sectional study was performed at Gastroenterology clinics affiliated with ...
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Introduction: The present study was conducted to evaluate the prevalence of trend and use of complementary and alternative medicine in patients referring to the Gastroenterology clinics in Mashhad. Methods: The present cross-sectional study was performed at Gastroenterology clinics affiliated with Mashhad University of Medical Sciences. The study began in December 2015 and ended in March 2017. The study subjects (n=751) were randomly selected from patients referring to Gastroenterology clinics in the city of Mashhad. Patients responded to the questions through interviews. The collected data were analyzed by SPSS-16 statistical software.Results: This study was conducted on 751 patients referring to gastroenterologists; of whom, 274 (48.36%) were male and 476 (38.63) were female. According to the results, the most popular complementary and alternative medicine treatments were respectively herbal medicine, cupping therapy and acupuncture. A significant difference was observed in the means at is faction with complementary and alternative medicine between those who believed in it and those who did not (p=0.001); but, no significant difference was detected in mean satisfaction with complementary and alternative medicine between patients with different occupations (p=0.193). There was also a significant difference in the number of patients between the group of patients receiving chemical medication and the group of patients receiving complementary and alternative medicine therapies (p=0.005). No significant difference was found in the level of satisfaction with complementary and alternative medicine between participants referring to the Gastroenterology clinics for different causes (p=0.431); nonetheless, the highest satisfaction was observed in patients with malignancy, and the lowest satisfaction was detected in patients with esophageal disorders.Conclusion: This study indicated the high prevalence of complementary and alternative medicine in Iran. The worldwide popularity of complementary and alternative medicine should not be overlooked, therefore; current medical treatment systems need to be revised and modified
Raheleh Jabini; Arezoo Mirbolouk; mohamadreza farzanehfar
Abstract
Introduction: This study aimed to evaluate the mRNA expression of cyclooxygenase-2 (Cox-2) in ascites caused by various diseases. Moreover, it was attempted to investigate its usefulness in the differential diagnosis between malignant and benign ascites.
Methods: A total of 52 ascitic fluid samples ...
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Introduction: This study aimed to evaluate the mRNA expression of cyclooxygenase-2 (Cox-2) in ascites caused by various diseases. Moreover, it was attempted to investigate its usefulness in the differential diagnosis between malignant and benign ascites.
Methods: A total of 52 ascitic fluid samples were collected from cirrhotic patients referred to Ghaem Hospital affiliated to Mashhad University of Medical Sciences, Mashad, Iran. Subsequently, the samples were divided into two experimental groups, namely benign ascites (n=26) and malignant ascites (n=26). Reverse transcriptase-polymerase chain reaction (RT-PCR) was utilized to determine the presence of Cox-2 mRNA in samples.
Results: According to the results, the mean age of the patients was 56.94±12.04 years (age range: 30-80 years), and the majority of the patients were male (1.88 to 1). There was no significant difference between the two groups in terms of age and gender. The Cox-2 mRNA was detected in 4 (15.4%) and 15 (57.7%) patients from the benign and malignant groups, respectively (P=0.003). Moreover, the sensitivity, specificity, as well as positive and negative predictive values of Cox2 to differentiate malignant from benign ascites were estimated at 57.7%, 84.6%, 78.9%, and 66.7%, respectively.
Conclusion: The Cox2 mRNA expression assessed by RT-PCR could be a useful method in differential diagnosis and screening of malignant ascites.
Raheleh Jabini; Seyed Musa al-Reza Hosseini; Maryam Shirdeli; Ali Alabaf Yousefi; Mohamadreza Farzanehfar
Abstract
Introduction: Gallbladder stone and sludge are common diseases worldwide. The causes of gallbladder stone and sludge are numerous. Since some studies have reported the effects of thyroid hormones on the function of the sphincter of Oddi and biliary discharge, the present study aimed to evaluate hypothyroidism ...
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Introduction: Gallbladder stone and sludge are common diseases worldwide. The causes of gallbladder stone and sludge are numerous. Since some studies have reported the effects of thyroid hormones on the function of the sphincter of Oddi and biliary discharge, the present study aimed to evaluate hypothyroidism as a risk factor for gallbladder stone formation.Methods: This case-control study was conducted on patients whose sonography indicated gallbladder sludge or stone and those referring to our clinic with pain in the right upper quadrant of the abdomen. All the patients were initially examined by a sonologist to confirm gallbladder stone and sludge. Afterwards, thyroid function tests (TSH, T4, and T3RU via radioimmunoassay) were requested for the patients, and the results were analyzed and compared with the control group.Results: Among 318 patients, 171 (53.77%) were male. In the case group, six females (8.4%) and 10 males (11.2%) had hypothyroidism. Overall, 9.9% of the patients (n=16) had hypothyroidism. In the control group, the prevalence of hypothyroidism was 2.5% (n=4) (OR: 2.082; 95% CI: 1.022-11.046; P=0.017). In the case group, 4.3% (n=7) had subclinical hypothyroidism, and 5.6% (n=9) had clinical hypothyroidism, while in the control group, only 1.9% of the patients (n=3) showed signs of subclinical hypothyroidism, and 0.6% (n=1) showed signs of clinical hypothyroidism. In the patients with gallbladder sludge and stone, the prevalence of clinical hypothyroidism was higher than subclinical hypothyroidism.Conclusion: According to the results, hypothyroidism was prevalent in the patients with gallbladder stone and sludge. Therefore, it is recommended that the thyroid function of patients with gallbladder stone and sludge be examined even if the patients do not harbor any other risk factors for the disease.
Mohamadreza Farzanehfar; Homeyra Ommati; Raheleh Jabini; Mahdi Zardadi
Abstract
This study aimed to describe the case of a young woman presenting with abdominal pain, nausea, and vomiting three month after intragastric balloon placement. The patient was diagnosed with acute pancreatitis based on clinical findings, laboratory data, and imaging results. During endoscopy, the balloon ...
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This study aimed to describe the case of a young woman presenting with abdominal pain, nausea, and vomiting three month after intragastric balloon placement. The patient was diagnosed with acute pancreatitis based on clinical findings, laboratory data, and imaging results. During endoscopy, the balloon was dislodged and obstructed in the second portion of the duodenum. After the removal of the balloon, all the symptoms of the patient were resolved, and she was discharged.