Clement A Adepiti; Akaninyene Eseme Ubom; Ibraheem Olayemi Awowole; Kayode Olusegun Ajenifuja
Abstract
Introduction: Placental site trophoblastic tumor (PSTT) is a rare form of gestational trophoblastic disease (GTD) that is usually associated with high mortality compared to the other subtypes because of its unpredictable biological behavior, less responsiveness to chemotherapy, and poor prognosis. Case ...
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Introduction: Placental site trophoblastic tumor (PSTT) is a rare form of gestational trophoblastic disease (GTD) that is usually associated with high mortality compared to the other subtypes because of its unpredictable biological behavior, less responsiveness to chemotherapy, and poor prognosis. Case Presentation: We present a 27year old nulliparous lady referred to our centre for recurrent vaginal bleeding following two evacuations for an incomplete spontaneous miscarriage after eight weeks of amenorrhea. Her assessment revealed low serum beta-human chorionic gonadotropin (βhCG) and high human placental lactogen (hPL) levels. Ultrasound scan and Doppler study showed a highly vascular tumor infiltrating the myometrium. She strongly desired to preserve her fertility and was initially commenced on low dose Methotrexate with marginal reduction in tumor volume and resistance on higher dose. She responded well to combination chemotherapy and the tumor disappeared after the second course. She received three additional courses and was followed up with serial ultrasonography for one year. She subsequently conceived spontaneously, with vaginal delivery of a live, normal female baby at term. Conclusion: Though hysterectomy combined with chemotherapy is the recommended management for PSTT and serum hPL is the usual tumor marker for follow-up, we present a case of successful treatment with combination chemotherapy alone and follow-up with subsequent cure, spontaneous conception, and delivery of a live baby.
Abulqasem Kosari
Abstract
Renal transplantation was considered as an efficient and ideal method for end stage renal disease treatment of the patients, by accomplishment of the first successful transplantation in 1954 (Boston USA). Renal transplantation has transmuted the treatment of choice in end stage renal disease, along with ...
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Renal transplantation was considered as an efficient and ideal method for end stage renal disease treatment of the patients, by accomplishment of the first successful transplantation in 1954 (Boston USA). Renal transplantation has transmuted the treatment of choice in end stage renal disease, along with prolonging survival; it offers high quality with low morbidity. Imaging modalities play an important role in the diagnosis of complications arising in renal transplant. Color Doppler ultrasound is the first-line imaging modality for evaluation of renal graft. Computed tomography scan in parallel with magnetic resonance imaging and digital subtraction angiography are used as problem-solving tools in indetermination of cases. Interventional radiology such as transluminal angioplasty has an important role in management of complications. Use of real time ultrasound guidance for percutaneous biopsy is almost universal.
Maral Sadrolodabaei; Behrouz Davachi; Mahdi Silanian Toosi
Abstract
Liver metastatic disorders usually occur in patients with stomach, pancreas, breast, colon, and lung and etc tumor. About 30 percent of patients die because of malignancies, have liver metastases. Liver imaging examination is a fundamental preclinical test to predict patient’s prognosis and is ...
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Liver metastatic disorders usually occur in patients with stomach, pancreas, breast, colon, and lung and etc tumor. About 30 percent of patients die because of malignancies, have liver metastases. Liver imaging examination is a fundamental preclinical test to predict patient’s prognosis and is required to monitor treatment. Despite recent advances in radiologic examination, liver metastases are still remaining as a challenge in human oncology. It seems that US is a reliable alternate for CT scan in metastases detection. CT scan should be considered in patients are highly suspension for liver metastases, who have normal or undetermined US findings. The aim of this study was a brief review of radiologic assessment in liver metastases.