Document Type : Original article


1 MSc in Nutritional Sciences, Member of Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

2 Associate Professor, Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

3 MD, PhD candidate in Nutritional Sciences, Department of Nutritional Sciences, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

4 Assistant Professor, Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

5 Associate Professor, Department of Statistics, Faculty of Mathematical Sciences, Ferdowsi University of Mashhad, Mashhad, Iran

6 Associate Professor, Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

7 Professor of Nutritional Sciences, Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

8 Biochemistry and Nutrition Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran


Introduction:Gastric bypass surgery is an intervention used to treat class III obesity and its complications. Evidence is scarce regarding its benefits among the Iranian population, especially its role in resolving obesity-related complaints and comorbidities. The present study aimed to investigate the impact of gastric bypass surgery on the improvement of obesity-related complaints and comorbidities in morbid obesity.
Methods:This study was conducted on 35 morbidly obese patients who volunteered to undergo gastric bypass surgery. Anthropometric data, comorbidity status, and dietary habits were collected at baseline and six months postoperatively. Data analysis was performed in SPSS version 16.0.
Results: The majority of the patients were female (80%). A significant difference was observed in the frequency distribution of normal dietary habits (five regular meals per day) before and after surgery (P = 0.01). In comparison, the distribution was not significant for snacking and three large meals per day (P > 0.05). All complaints of eating disorders according to self-reports (e.g., overeating and night eating syndrome) significantly improved (P < 0.05 ). Moreover, the dose of the medications prescribed for the comorbidities associated with obesity reduced significantly (P = 0.001). The frequency of several obesity-related complaints (e.g., knee pain, hirsutism, acanthosis nigricans, and sleep apnea) also decreased significantly (P < 0.05). However, no significant improvement was observed in hair loss, brittle nails, and menstrual dysfunction (P > 0.05).
Conclusion: Accordingly, gastric bypass surgery could improve obesity-related complaints six months postoperatively. Also, according to the patients’ self -declaration, patients’ adherence to “normal eating habits” increased during this period, and their eating disorders like night eating syndrome (NES) and overeating behaviors decreased compared to before the surgery.


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