Document Type : Case series

Authors

1 4. Toxicological Research Center, Excellence Center of Clinical Toxicology, Department of Clinical Toxicology, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

2 1. Social Determinants of Health Research Centre, Shahid Beheshti University of Medical Sciences, Tehran, Iran 2. Department of Clinical Toxicology, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

3 School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

10.22038/rcm.2022.64158.1399

Abstract

Background: paraquat is a cheap and easy access herbicide which its intoxication is limited in Iran.

Objectives: The current study aims to provide some epidemiologic data within paraquat poisoning from the largest referral center of clinical toxicology in Iran.

Methods: In this study we investigated the paraquat poisoning patients who were admitted to Loghman-Hakim Hospital in Tehran, Iran from 2008 to 2016

Results: A Total of 12 patients participated in this study, 50% of these patients were between 10-20 years old, 41.7% were between 26-40 years old, and 8.3% were above 55 years old. About 83.3% were male and 16.7% were female. Treatments which were given in the hospital include cyclophosphamide (58.3%), cortisol (75%), vitamin C (50%), vitamin E (83.3%), N-acetyl cysteine (83.3%). among the hospitalized patients, 66.6% of the patients needed invasive interventions to maintain the airways, of which 3.33% underwent tracheostomy and the same amount underwent intubation. Among the patients, the number of deaths was 5, among whom 3 died due to pulmonary and kidney failure.

Conclusions: This study indicates that the majority are younger than 40 years and males. Prevention and limited access to this substance in necessary due to the lack of antidote.

Keywords