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Psychological Function and Serum Vitamin D Concentration in COVID-19 Patients: A cross-sectional study

Document Type : Original article

Authors

1 Department of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

2 Department of Nutrition, Food Sciences and Clinical Biochemistry, School of Medicine, Social Determinants of Health Research Center, Gonabad University of Medical Science, Gonabad, Iran

3 Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

4 Metabolic Syndrome Research Center. Mashhad University of Medical Sciences, Mashhad, Iran.

5 5International UNESCO Center for Health Related Basic Sciences and Human Nutrition, Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

6 Department of Medical Education, Brighton and Sussex Medical School, Falmer, Brighton, UK.

7 Biochemistry and Nutrition Research Center and Department of clinical biochemistry, Mashhad University of Medical Sciences, Mashhad, Iran

Abstract

Introduction: The pandemic of COVID-19 created a psychological response. So, the psychological function of COVID-19 patients is an important subject that forces us to follow up with them.
Aim: Assess the correlation between vitamin D serum concentrations and psychological functions such as insomnia, stress, and depression through the COVID-19 pandemic
Methods: In this cross-sectional study, blood samples from 120 COVID-19 patients (61 males and 59 females) who had more than 30 years, were taken. Also, 25(OH)D Serum level of COVID-19 patients was analyzed. The Insomnia Severity Index (ISI), Depression anxiety stress scales (DASS), and the Short Form Health Survey (SF-36) were used to analyze insomnia, anxiety, stress, quality of life, and depression.
Results: The relationship between temperature (p=0.039), PCO2 (p=0.022), and serum vitamin D level was significant. Additionally, there was a significant correlation between stress (p=-0.023, OR=0.389, 95% CI for OR=0.047, 0.843), depression (p=0.012, OR=0.659, 95% CI for OR=0.476, 0.913), and the concentration of serum vitamin D.
Conclusion:This study recommends that vitamin D supplementation improve psychological state in COVID-19 patients.

Keywords

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Reviews in Clinical Medicine
Volume 10, Issue 3
September 2023
Pages 6-12
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