Reviews in Clinical Medicine

Reviews in Clinical Medicine

An Update on Ocular Trauma in Children with Behavioral Disorders

Document Type : Review

Authors
1 Eye Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
2 Psychiatry and Behavioral Sciences Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Abstract
Ocular trauma is a major cause of visual impairment in children, and those with behavioral disorders may be at greater risk because of impulsivity, limited hazard awareness, and difficulty adhering to safety instructions. This narrative review provides an updated overview of the epidemiology, risk factors, clinical presentations, and management of ocular trauma in children with behavioral disorders, with emphasis on prevention strategies and long-term outcomes. A comprehensive literature search was conducted to identify studies investigating the association between behavioral disorders, such as attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and conduct disorders, and ocular injuries in children. The available evidence was synthesized to highlight recent findings, clinical challenges, and advances in management approaches. Children with behavioral disorders appear to have a higher incidence of ocular trauma and often present with more severe injuries, partly because of delayed recognition and treatment. Common causes include accidental self-inflicted injuries, falls, and object-related trauma. Diagnostic and management challenges arise from communication difficulties, sensory sensitivities, and limited behavioral cooperation. Recent evidence suggests that tailored preventive interventions, caregiver education, and multidisciplinary management may reduce the burden of ocular trauma in this vulnerable population.
Keywords

1. Shariati MM, Eslami S, Shoeibi N, Eslampoor A, Sedaghat M, 
Gharaei H, et al. Development, comparison, and internal validation 
of prediction models to determine the visual prognosis of patients 
with open globe injuries using machine learning approaches. BMC
Medical Informatics and Decision Making. 2024;24(1):131. 
doi:10.1186/s12911-024-02583-0.
2. Shariati MM, Sahraei N, Kakhki MS. Trauma and 
chorioretinal shockwave injury from intra‑orbital foreign body. 
Clin Case Reports. 2023;12(1):e8360. doi:10.1002/ccr3.8360.
3. Kaçer EÖ, Kaçer İ. Ocular trauma in the pediatric age group: 
a systematic review. Egypt Ped Assoc Gazette. 2022;70(1):28. 
doi:10.1186/s43054-022-00137-8.
4. Ashby GB, Claxton MR, Kim EJ, Tanke LB, Butterfield SD, 
Bothun ED, et al. Incidence and clinical features of pediatric ocular 
trauma in a population-based cohort. J AAPOS. 2023;27(2):78. e1-
78. e6. doi:10.1016/j.jaapos.2022.12.004. 
5. Bućan K, Matas A, Lovrić JM, Batistić D, Borjan IP, Puljak L, 
et al. Epidemiology of ocular trauma in children requiring hospital 
admission: a 16–year retrospective cohort study. J Glob Health. 
2017;7(1):010415. doi:10.7189/jogh.07.010415.
6. Phan R, Smits DJ, Velez-Montoya R. Trauma: Introduction. 
Trauma. 2015.
7. Alabdulkader B, Alsiwat Y, Almatar H, Albdah B, Almustanyir 
A, Almutleb E, et al. Prevalence, characteristics, and management 
of pediatric ocular trauma in Riyadh, Saudi Arabia: a retrospective 
analysis. Healthcare (Basel). 2024;12(10):1054. 
doi:10.3390/healthcare12101054.
8. Choudhury R, Naseer S, Hale E. Ocular trauma in patients 
with ADHD. Invest Ophthalmol Vis Sci. 2024;65(7):2874. 
doi:10.1167/iovs.65.7.2874.
9. Kafali HY, Biler ED, Palamar M, Ozbaran B. Ocular injuries, 
attention deficit and hyperactivity disorder, and maternal 
anxiety/depression levels: is there a link? Chin J Traumatol. 
2020;23(2):71-7. doi:10.1016/j.cjtee.2019.12.006.
10. Bayar H, Coskun E, Öner V, Gokcen C, Aksoy U, Okumus S, et 
al. Association between penetrating eye injuries and attention 
deficit hyperactivity disorder in children. Br J Ophthalmol. 
2015;99(8):1109-11. doi:10.1136/bjophthalmol-2014-306362.
11. Lee YH, Lenhart PD, Lambert SR. Cataract secondary to selfinflicted blunt trauma in children with autism spectrum disorder. 
J AAPOS. 2016;20(4):361-2. doi:10.1016/j.jaapos.2016.04.009.
12. Felfeli T, Mireskandari K. Eye complications from self-injury 
in a child. CMAJ. 2018;190(4):E114-E115. 
doi:10.1503/cmaj.170792.
13. Little JA. Vision in children with autism spectrum disorder: 
a critical review. Clin Exp Optom. 2018;101(4):504-13. 
doi:10.1111/cxo.12615.
14. Swenson AK, Nies MA, Taylor N, Maughan D. Baseline 
concussion testing in high school athletes: a gap between policy 
and practice. J Dr Nurs Pract. 2025. doi:10.1891/JDNP-2024-0033.
15. de los Santos M, Eslava VH, Guerra MA, Lozano-Ramirez JF, 
Enriquez J, Martinez AP, et al. Applied behavior analysis in Mexico: 
efforts and challenges in public policy, advocacy, and autism 
intervention. Behav Anal Pract. 2025;18:1-10. 
doi:10.1007/s40617-024-00904-1.
16. Sadeghi J, Sedaghat M, Abadi MKA, Motamed Shariati M. 
Immediate bilateral sequential keratoplasty in a 13-year-old boy 
with perforated corneal ulcer secondary to exposure keratopathy. 
Clin Case Rep. 2025;13(10):e71273. doi:10.1002/ccr3.71273.