Mitra Ahadi; Ali Beheshti Namdar; Samaneh Bakhshi; Elham Mokhtari Amirmajdi; Mohammad Derakhshan; Atieh Yaghoubi; kiarash Ghazvini
Abstract
Introduction: Based on serological studies, the prevalence of Helicobacter pylori infection in Iranian adults is up to 80%. Gastritis, peptic ulcer, and gastric adenocarcinoma are common clinical outcomes of this infection in Iran. Since antibiotic resistance patterns of Helicobacter pylori are geographically ...
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Introduction: Based on serological studies, the prevalence of Helicobacter pylori infection in Iranian adults is up to 80%. Gastritis, peptic ulcer, and gastric adenocarcinoma are common clinical outcomes of this infection in Iran. Since antibiotic resistance patterns of Helicobacter pylori are geographically different, local studies are highly required.Methods: Eighty isolates of Helicobacter pylori were obtained from patients referred to the endoscopy unit of Ghaem Hospital in Mashhad. Demographic features including age, gender, and symptoms were recorded before the sampling. The antibiotic susceptibility patterns of isolates were determined for the five common antibiotics used for the treatment of Helicobacter pylori infection. The agar dilution method was used to evaluate the antibiotic resistance patterns.Results: The patterns of antibiotic resistance were determined, and 41.2%, 13.7%, 8.7%, 6.6%, and 6.6% of isolates were resistant to metronidazole, clarithromycin, amoxicillin, tetracycline, and furazolidone, respectively.Conclusion: Our study demonstrates that the overall rate of antibiotic resistance of Helicobacter pylori especially in the case of metronidazole has increased over time. The resistance rates are generally higher in the age range of 30-60 years and in females for the case of metronidazole. This reminds us of the need for a continuous monitoring program of antibiotic susceptibility patterns.
Kobra Salimiyan rizi; Kiarash Ghazvini; Hadi Farsiani
Abstract
Enterobacter spp. is a gram-negative environmental bacterium, which belongs to the Enterobacteriaceae family and is found in water, sewage, soil, and plants. These bacteria are common among humans and animals, and the most frequently isolated species is Enterobacter cloacae. The species of this genus ...
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Enterobacter spp. is a gram-negative environmental bacterium, which belongs to the Enterobacteriaceae family and is found in water, sewage, soil, and plants. These bacteria are common among humans and animals, and the most frequently isolated species is Enterobacter cloacae. The species of this genus are often opportunistic pathogens with expanding significance in nosocomial infections, particularly in neonates, immunocompromised patients in intensive care units, emergency sections, skin and soft tissue infection wards, and urology wards. With the unexpected and rapid increase in antibiotic resistance in various bacterial species, there has been a new alarm for the health of the human community. Enterobacter species cause pneumonitis, bacteremia, post-neurosurgical meningitis, neonatal meningitis, skin and soft tissue infections, and urinary tract infections. Some of the main risk factors for the occurrence and dissemination of Enterobacter spp. infections are poor hand hygiene, crowding, low birth weight, premature birth, intubation of patients, prolonged hospital stay, contaminated infant formula, intravenous feeding, use of extended-spectrum antibiotics and use of intravenous catheters.