Omid Pouresmaeil; Jalal Mardaneh
Abstract
AbstractPantoea agglomerans is a Gram-negative rod that forms aggregates in liquid media. It is known for causing opportunistic infections in humans, especially in hospital settings and wounds from plant materials. The bacterium can lead to various infections like arthritis, endophthalmitis, and bacteremia, ...
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AbstractPantoea agglomerans is a Gram-negative rod that forms aggregates in liquid media. It is known for causing opportunistic infections in humans, especially in hospital settings and wounds from plant materials. The bacterium can lead to various infections like arthritis, endophthalmitis, and bacteremia, often from wooden splinters or plant thorns. Infections are diverse and affect immunocompromised individuals but respond well to antibiotics. P. agglomerans can be identified by its morphological characteristics and growth preferences in the lab. Resistance to Fosfomycin can aid in identification. Treatment typically involves antibiotics like imipenem and fluoroquinolones. Hospital-acquired infections from P. agglomerans have been linked to scenarios like endocarditis and septicemia. Selective culture media are crucial for isolating Pantoea species from clinical specimens. Regarding the treatment of infections induced by P. agglomerans, it is noteworthy that this bacterium generally exhibits susceptibility to a broad spectrum of antibiotics. Notably, these include but are not limited to imipenem, fluoroquinolones (e.g., ciprofloxacin and ofloxacin), aminoglycosides (e.g., amikacin, gentamicin, and tobramycin), broad-spectrum cephalosporins, and trimethoprim-sulfamethoxazole
Mahbobeh Khammar; Sepideh Hassanzadeh; Fatemeh Tara; Malihe Siahsar; Fatemeh Tahmasbi; Masoud Keikha; Kiarash Ghazvini
Abstract
Introduction:In the present study, we evaluated the 4-year antimicrobial resistance trends of several nosocomial pathogens during 2018-2021 in a reffereal Mashhad hospital, Mashhad, Iran.
Methods:In this study, we reviewed the data of 70,234 clinical isolates were registred Infection Control Data of ...
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Introduction:In the present study, we evaluated the 4-year antimicrobial resistance trends of several nosocomial pathogens during 2018-2021 in a reffereal Mashhad hospital, Mashhad, Iran.
Methods:In this study, we reviewed the data of 70,234 clinical isolates were registred Infection Control Data of Ghaem Hospital, Mashhad, Iran. The antimicrobial susceptibility testing was performed using Kirby-Bauer disk diffusion method according to clinical and laboratory standard institute (CLSI) instructions to evaluate trends of antimicrobial resistance over the times.
Results: There were identified (A. baumannii: n = 19,374; K. pneumonia n = 17,206; E. coli n = 23,777; S. epidermidis: n = 9,877). We did not find any significant difference in changes of antimicrobial trends over the time except in minor cases . However, The pattern of antimicrobial drug resistance was gradually differed except E. coli.
Conclusion: our results suggested the overall antimicrobial resistance trends was remins the same level during 2018-2021. It seems that in accessibility and stop prescribing of antibiotics can lead to decreasing antibiotic resistance rate.