Genetic diversity of clinical isolates of Mycobacterium tuberculosis in Northeast of Iran

Samaneh Saedi; kiarash ghazvini; Masoud Youssefi; Hadi Safdar; saman soleimanpour; Parviz Afrough; Amir Azimian; hamid solgi; Masoud Keikha

Volume 11, Issue 1 , March 2024, , Pages 8-12

  AbstractBackground: Mycobacterium tuberculosis is still one of the most dangerous human pathogens. Identification of the relationships between different clinical strains has remained a high priority for epidemiology research. Methods: In this study, we used MLSA (Multilocus sequence analysis) to generate ...  Read More

Evaluation of Interleukin 33 and ST2 Serum Concentration in Active Tuberculosis Patients

Masoud Youssefi; Golsa Teimouri; Farnaz Zahedi Avval; kiarash ghazvini; Masoud Keikha

Volume 8, Issue 3 , September 2021, , Pages 106-110

  The aim of this study was to determine the serum levels of ST2 protein and interleukin-33 in patients affected to tuberculosis and compare them with the control group. In the present study, at first 30 patients affected to TB were randomly selected and 52 healthy individuals, who were matched with respect ...  Read More

A 4-year Study on Antimicrobial Susceptibility Trends of Nosocomial Infections in a Mashhad Referral Hospital, Mashhad, Iran

Mahbobeh Khammar; Sepideh Hassanzadeh; Fatemeh Tara; Malihe Siahsar; Fatemeh Tahmasbi; Masoud Keikha; Kiarash Ghazvini

Volume 8, Issue 2 , June 2021, , Pages 50-55

  Introduction:In the present study, we evaluated the 4-year antimicrobial resistance trends of several nosocomial pathogens during 2018-2021 in a reffereal Mashhad hospital, Mashhad, Iran. Methods:In this study, we reviewed the data of 70,234 clinical isolates were registred Infection Control Data of ...  Read More

High Salt Intake in Helicobacter Pylori Infected Individuals Can Significantly Increase the Risk of Gastric Cancer; a Global Analysis

kiarash Ghazvini; Masoud Keikha

Volume 8, Issue 1 , March 2021, , Pages 41-43

  The odds ratio with 95%CIs was used to evaluated the synergistic effects between high salt intake and H. pylori infection among gastric cancer cases. Heterogeneity was assessed by I2 index and Cochrane Q-test; In addition, the presence of publication bias was measured using Begg’s p-value and Egger’s ...  Read More

Tuberculosis for Alzheimer’s: Risk Factor, Treatment or Prevention

Atieh Yaghoubi; kiarash Ghazvini; Seyed Isaac Hashemy

Volume 7, Issue 3 , September 2020, , Pages 119-122

  Alzheimer's disease is a type of dementia and there were 50 million individuals have dementia in 2018 worldwide and the cost of dementia care to Medicare and Medicaid is so high (about US$1 trillion) in that year. Recently, several articles show that tuberculosis may be increased the development rate ...  Read More

IL-33/ST2 Axis as a Well-Known Endogenous Defense Against Tuberculosis

Mohsen karbalaei; Kiarash Ghazvini; Masoud Keikha

Volume 7, Issue 3 , September 2020, , Pages 127-133

  Tuberculosis (TB) infection is caused by an intracellular bacterium, Mycobacterium tuberculosis (Mtb). The disease is among the most important infectious diseases, which has dedicated most cases of morbidity and mortality to itself worldwide. The global report of World Health Organization (WHO) in 2019 ...  Read More

Colistin Resistance Burden among Clinical Isolates of Gram-negative Rods: A Systematic Review and Meta-analysis

Razieh Amirfakhrian; Atieh Yaghobi; Roya Saddat Ghaderi; Seyed Isaac Hashemy; Kiarash Ghazvini

Volume 7, Issue 2 , June 2020, , Pages 48-70

  Introduction: In recent decades, the inappropriate use of antibiotics and the existence of transferable resistant elements have caused the emergence of multidrug-resistant (MDR) gram-negative organisms. Antimicrobial resistance is becoming one of the major challenges to public health and has caused morbidity ...  Read More

The evaluation of the microbial community of lower respiratory tracts microbiota in tuberculosis patients and healthy individuals using Metagenomics

kiarash ghazvini; Masoud Youssefi; Masoud Keikha

Volume 7, Issue 2 , June 2020, , Pages 83-86

  Introduction: Tuberculosis is remained as global challenge which is considered as the top cause of human death in worldwide. The presence of lower respiratory tracts microflora can modulate immune response and play important role in susceptibility to TB. The aim of study was comparison ...  Read More

The evaluating expression profile of virulence factors in Helicobacter pylori strains by system biology; an example from Colombia

kiarash ghazvini; Masoud Youssefi; Masoud Keikha

Volume 7, Issue 2 , June 2020, , Pages 87-94

  Abstract Helicobacter pylori is one of the most common bacteria in the stomach, colonizing about one-half of the population in the world, while most of them remain asymptomatic throughout their lives and gastric cancer (GC) occurs in only 1-2% of people. It seems that the final outcomes of Helicobacter ...  Read More

Autophagy as one of the most important strategies for the treatment of tuberculosis; Mini-review

Masoud Youssefi; Majid Eslami; Mohsen Karbalaei; Masoud Keikha; Kiarash Ghazvini

Volume 6, Issue 4 , November 2019, , Pages 135-139

  Cancer is defined as uncontrolled cell division, which could spread or invade various tissues. There are more than 200 types of cancer, including breast, skin, lung, colon, and prostate cancer, and lymphoma, the symptoms and indications of which vary depending on the type of tissues. Cancer has several ...  Read More

Prediction of Tuberculosis Using a Logistic Regression Model

Kiarash Ghazvini; Shamsoddin Mansouri; Mohammad-Taghi Shakeri; Masoud Youssefi; Mohammad Derakhshan; Masoud Keikha

Volume 6, Issue 3 , September 2019, , Pages 108-112

  Introduction: Tuberculosis (TB) is a chronic bacterial disease and a leading cause of mortality among single-agent infectious diseases following the human immunodeficiency virus infection across the world. Logistic regression is a method of statistical analysis with predictive capability. This multivariate ...  Read More

Cutaneous anthrax in the northeast of Iran: A case report and review of the literature

Mohsen Karbalaei Zadeh Babaki; Mahdis Ghavidel; Hadi Farsiani; Kiarash Ghazvini

Volume 5, Issue 1 , February 2018, , Pages 26-28

  Bacillus anthracis is an aerobic, gram-positive, and spore-forming Bacillus species. The most common form of anthrax infection is the cutaneous form. The infection usually develops several days after exposure to products of infected animals and manifest as black sore with severe swelling on the skin.A ...  Read More