Original article
Anjani Kumar Srivastava; Anjali Singh; Basavaraj S Mannapur; ANUJ SINGH
Abstract
Introduction: Low birth weight (LBW) is a challenging multifaceted public health problem as it associated with infant mortality. LBW affects newborns’ survival and is a global concern especially for developing countries. It is the most common health indicator for assessing neonates’ health ...
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Introduction: Low birth weight (LBW) is a challenging multifaceted public health problem as it associated with infant mortality. LBW affects newborns’ survival and is a global concern especially for developing countries. It is the most common health indicator for assessing neonates’ health conditions. In terms of short and long term consequences, LBW plays an important role in inferring infant and childhood morbidities such as mental retardation, learning disabilities, inhibited growth and cognitive delays and so on.Objective: To estimate the prevalence of LBW babies and determine the socio-demographic factors associated with LBW. Methods: A community-based cross-sectional study was carried out among postnatal mothers with singleton live born baby in a rural area of North Karnataka, India from January 2016 to December 2016. Based on the sample size, data was collected from 337 participants. The study Participants comprised of postnatal mothers with single live born baby. Weight of the newborn was recorded. Chi square test was used to find the association. Results: The prevalence of LBW was found to be 21.1%. A number of factors like teenage pregnancy, occupation, type of family, etc. were found to be significantly associated with low birth weight.Conclusion: Although the prevalence of LBW is lower than some of the studies done earlier in other parts of the country, but it are still more than national average of 18.6%. Thus there is a need to encourage the utilization of health services to ensure 100% antenatal care (ANC) registration and institutional deliveries.
Original article
Ziya Asan
Abstract
Introduction: A correlation cannot be established between clinical findings and hematoma thickness in Chronic Subdural Hematoma cases. The effects of hematoma on intracranial structures can be evaluated as a grading criterion. This study aims to establish a grading system by establishing a correlation ...
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Introduction: A correlation cannot be established between clinical findings and hematoma thickness in Chronic Subdural Hematoma cases. The effects of hematoma on intracranial structures can be evaluated as a grading criterion. This study aims to establish a grading system by establishing a correlation between the compression effects of hematoma and clinical conditions in Chronic Subdural Hematoma cases.Methods: The radiological and clinical findings of the cases diagnosed with Chronic Subdural Hematoma were recorded. Headache, dizziness, focal neurological deficit, and reduction in Glasgow Coma Scale scores were recorded as clinical criteria. Radiologically, a 4-grade grading system was prepared. Hematoma without compression effect, dural compression and sulcus effacement, parenchymal compression, and midline shift of more than 5 mm were used in the grading system, respectively. The clinical symptoms and signs within each grade were recorded.Results: Computed Tomography examinations and clinical findings of 414 cases were recorded. It has been noted that as the grade increases, the clinical symptoms and signs increase along with the increase in hematoma thickness. However, it has been noted that an absolute correlation cannot always be established between hematoma thickness and clinical symptoms.Conclusion: The grading system is instructive in showing the effects of hematoma on intracranial structures rather than hematoma thickness in Chronic Subdural Hematoma cases. Complete drainage of hematoma is rare in surgically treated cases. Clinical improvement is associated with optimal intracranial dynamics rather than hematoma thickness. The grading system is instructive regarding clinical and radiological follow-up of the cases.
Original article
Alireza Sedaghat; Benyamin Fazli; arash peivandi; Farzaneh Fazeli; Bita Mirzaie Feyzabadi
Abstract
Background and Aim: This study was aimed to evaluate the prognosis of patients with severe burns by measuring the plasma base excess and serum lactate levels and comparing it with the ABSI scoring system as an important indicator in the resuscitation of burn patients.Methods: This prospective cohort ...
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Background and Aim: This study was aimed to evaluate the prognosis of patients with severe burns by measuring the plasma base excess and serum lactate levels and comparing it with the ABSI scoring system as an important indicator in the resuscitation of burn patients.Methods: This prospective cohort study was performed on all patients hospitalized in the burn ward of the hospital. The demographic data and ABSI scoring of all patients were recorded. Patients' clinical information and routine tests, gasometry (for measuring plasma base excess) and serum lactate levels were measured at the time of admission, 12 hours, and 24 hours after admission.Results: A total of 311 burning patients were evaluated in this study. Mann-Whitney test showed a significant difference in the mean plasma BE1 (at the time of admission) and BE2 (24 hours after admission) between the patients who were discharged and the patients who died (P <0.001). The results indicated a difference in the process of lactate changes between two groups of patients in terms of intensity of ABSI(P <0.001). The multivariate logistic regression with the entry of BE and lactate at the time of admission and ABSI as predictive variables indicated a significant BE and ABSI.Conclusion: The results of this study confirmed that the plasma base excess can be used as a valuable tool in the monitoring of burn patients' resuscitation along with clinical criteria. On the other hand, the ABSI scoring system is still a valuable tool to predict the deaths of burn patients.
Review
Saeedeh Talebi; Payam Sharifan; Andisheh Norouzian Ostad; Seyedeh-Elaheh Shariati; AmirAli Moodi Ghalibaf; Mehdi Barati; Malihe Aghasizadeh; Sahar ghoflchi; Hamideh Ghazizadeh; Niloofar Shabani; Gordon A. Ferns; Hamid Reza Rahimi; majid Ghayour
Abstract
Introduction: Chamomile (Matricaria chamomilla L.), as widely used as a medicinal herb and is brewed beverages, and has been used for the treatment of several conditions. The evidence from in vitro, in vivo, and clinical studies suggests that chamomile and its many flavonoid components have anti-oxidant ...
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Introduction: Chamomile (Matricaria chamomilla L.), as widely used as a medicinal herb and is brewed beverages, and has been used for the treatment of several conditions. The evidence from in vitro, in vivo, and clinical studies suggests that chamomile and its many flavonoid components have anti-oxidant and anti-inflammatory properties. This review aimed to provide an overview of the chemical constituents of chamomile and the effectiveness of the chamomile preparations and several of its constituents for the treatment of several medical conditions. Methods: The present comprehensive review study was conducted by searching electronic databases including Scopus, Web of Sciences, Embase, and PubMed, using relevant keywords. Results: Both animal and human studies indicate the positive effects of chamomile on the antioxidant enzyme activity. However, the mechanisms involved in the action of chamomile against the production of ROS remain still unknown. When it comes to its anti-inflammatory properties, a number of in vitro, in vivo, and clinical investigations have been reported regarding to the selective inhibition of COX-2, suppression of NO production, prevention of IL-1β, IL-6 and TNFα-induced NO levels, reduction of iNOS mRNA and protein expression, impediment of leukocyte adhesion and adhesion protein up-regulation in human endothelial cells, and blockage of IL-1 α-induced prostaglandin production, TNF-α-induced IL-6 and IL-8 release. Conclusions: Current studies suggest that chamomile and its flavonoid components have anti-oxidant and anti-inflammatory properties. On the basis of the existing evidences, chamomile appears to ameliorate several diseases caused by oxidative stress as well as inflammatory reactions.
Original article
Forough Rakhshanizadeh; alireza khadembashi; Elahe Heidari; Negar Morovatdar; Atefeh Soltanifar
Abstract
Introduction:Child abuse and neglect is a public health challenge with lifelong consequences for survivors. Physicians’ knowledge regarding child abuse and neglect is essential for diagnosis, treatment, and timely referral to legal authorities. This study aimed to determine pediatric residents’ ...
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Introduction:Child abuse and neglect is a public health challenge with lifelong consequences for survivors. Physicians’ knowledge regarding child abuse and neglect is essential for diagnosis, treatment, and timely referral to legal authorities. This study aimed to determine pediatric residents’ and pediatricians’ knowledge and attitude regarding child abuse and neglect.Methods: In this cross-sectional study, pediatric residents› and pediatricians› knowledge and attitude regarding child abuse and neglect were measured using a standard questionnaire with confirmed validity and reliability. In this questionnaire, knowledge score ranged from 0 to 17, and attitude score ranged from 10 to 50. After collecting the questionnaires and calculating the scores, the information was entered into the SPSS software (version 22), and statistical analysis was performed.Results: A total of 80 participants, including 38 pediatric residents and 42 pediatricians, participated in this research. Among them, 71.3% were female, and 28.8% were male. The mean score of knowledge and attitude in all participants was 14.05 ± 1.88 out of 17 and 41.39 ± 4.36 out of 50, respectively. The mean score in the pediatric residents and pediatricians was 13.42 ± 2.02. and 14.62 ± 1.57 for knowledge and 40.66 ± 4.32 and 42.05 ± 4.35 for attitude, respectively. Regarding knowledge, 19 participants (23.8%) had a good score, 35 (43.8%) had a moderate score, and 26 (32.5%) had a poor score (p=0.24). There was a significant difference in terms of knowledge score among four academic groups (first-year resident, second-year resident, third-year resident, and pediatrician) (p=0.031), as the score wassignificantly higher in pediatricians than in residents (p=0.004). However, no significant difference was observed for attitude score (p=0.056). In general, and regarding all participants, no significant relationship was observed between attitude score and knowledge score (p=0.059).Conclusion: Most pediatric residents and pediatricians participating in the present study had moderate knowledge and attitude toward child abuse and neglect, and less than a quarter of the participants had good knowledge in this regard. Also, the pediatricians had significantly higher knowledge scores than the pediatric residents. These results emphasize the importance of more education for pediatric residents regarding child abuse and neglect and continuing education programs for pediatricians.
Original article
Reza Zare; Narges Ghazi; Farnaz Mohajertehran; Narges Asfiaee; Pendar Argani; Negar Khodaeni; Salehe Akhondian
Abstract
Introduction:Oral lichen planus treatment offers favorable clinical results over time due to its widespread prevalence. However, to date, there is still no theoretical agreement on the cause of this disease. Therefore, the present study aimed to investigate the frequency of human papillomavirus (HPV) ...
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Introduction:Oral lichen planus treatment offers favorable clinical results over time due to its widespread prevalence. However, to date, there is still no theoretical agreement on the cause of this disease. Therefore, the present study aimed to investigate the frequency of human papillomavirus (HPV) DNA in oral lichen planus (OLP) tissue samples by the polymerase chain reaction (PCR) method.Methods:This retrospective study was carried out from 1387 to 1398 on 40 OLP samples (24non-erosive-atrophic and 16 erosive-atrophic forms) in the Oral Pathology Department of Mashhad Dental School. Polymerase chain reaction (PCR) was undertaken to identify HPV-DNA. Subsequently, the samples for HPV-DNA underwent PCR analysis again with the specific primers. The data were analyzed statistically by chi-square and independent t-test test regarding the significance levelof lower than 0.05.Results: The population consisted of 29 women (72.5%) and 11 men (27.5%) with an average age of 49.48± 2.78 years. Human papillomavirus DNA in none of the studied samples (in none of the groups) was detected by PCR. Gender distribution in the studied groups was not significantly different from each other, as the groups did not differ significantly in average age.Conclusion: No HPV-positive samples were observed in oral lichen planus samples based on the recent findings in the current study of the Iranian population. Nevertheless, the patients› demographic data were not meaningfully associated. More sample sizes with a control group and a complete medical history should be recruited in further studies. Using complementary methods to approve the PCR method can help further studies to demonstrate accurate results.
Original article
Talat Khadivzadeh; Fatemeh Zahra karimi; Nahid Maleki
Abstract
Introduction: This study was conducted to determine the relationship between sex role and women's childbearing motivation.Methods: In this study 841 married female participants lived in urban society of Mashhad were recruited based on a multistage sampling from a variety of settings. Data was gathered ...
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Introduction: This study was conducted to determine the relationship between sex role and women's childbearing motivation.Methods: In this study 841 married female participants lived in urban society of Mashhad were recruited based on a multistage sampling from a variety of settings. Data was gathered using Childbearing Questionnaire (CBQ) and brief form of Bem sex role questionnaire. Analyzed using Pearson correlation coefficient, multiple regression test and independent t-test.Results: Feminine sex role was in significant relationship with positive childbearing motivation (p=.001). Masculine sex role have no relationship with both childbearing motivations. ANOVA showed a difference between the motivations in four groups of participants divided based on sex role scores. LSD test shows that positive motivation in android (p=.013) and masculine (p=.012) groups were significantly less than feminine group. Negative childbearing motivations in feminine group was less than in UN-differentiate group (p=.014). Conclusion: Multiple regression analysis show that positive motivation was in relationship with the feminine sex role and reverse relationship with marriage age. Reproductive health policy makers and family planning counselors can apply study findings in order to plan perfect programs to direct proper fertility behaviors in the society.