Original article
The effect of oral budesonide liquid therapy to alleviate clinical symptoms in patients with epidermolysis bullosa

Hamidreza Kianifar; Saeedeh Talebi

Volume 9, Issue 4 , December 2022, Pages 156-158


  Introduction: Epidermolysis bullosa is a genetic condition with skin fragility that leads to blister formation and erosion following minor trauma. This disease also involves the gastrointestinal tract by way of esophageal stricture and dysphasia. Some studies have recommended oral budesonide liquid therapy ...  Read More

Raoultella Infections from Clinical to Laboratory- Update & Literature review

Kobra Salimiyan rizi; Hadi Farsiani

Volume 9, Issue 4 , December 2022, Pages 159-171


  The genus Raoultella is still understudied compared to other Enterobacteriaceae members. However, there are numerous published case reports on Raoultella infections. The genetic closeness of Raoultella spp. and Klebsiella spp. may lead to misidentification using conventional microbiology methods. The ...  Read More

Polycystic ovary syndrome and inflammatory factors: Possible role of diet

Ava Hemmat; Faezeh Mashhadi; Mohsen Nematy; Nayere Khadem; Ezzat Hajmolla Rezaei; Fatemeh Roudi

Volume 9, Issue 4 , December 2022, Pages 172-176


  Polycystic ovary syndrome (PCOS) is the most common endocrinological disorder in women of reproductive age. Several studies have shown that inflammation factors have a crucial role in the function of the ovary as ovarian dysfunction can be caused by an imbalance of pro-inflammatory cytokines. Other studies ...  Read More

Case report
Meningitis with vancomycin-tolerant Streptococcus pneumonia: a case report in the northeast of Iran

Faria Hasanzadeh Haghighi; Hadi Farsiani; Mina Mostafavi; Mohammadhassan Aelami

Volume 9, Issue 4 , December 2022, Pages 177-180


  Meningitis is a clinical syndrome that occurs for a variety of reasons such as bacterial infections. Acute bacterial meningitis can occur at any age, and is a leading cause of mortality worldwide. Streptococcus pneumonia is a bacterial meningitis that can lead to pneumococcal meningitis, especially in ...  Read More

Case report
Prompt Reversing the Neurologic and Cardiac Manifestations of Valproate Poisoning by Hemodialysis: A Case Report

Ahmad Nemati; Farkhonde Nikkhah; Mohammad Moshiri; Hanie Salmani Izadi; Leila Etemad

Volume 9, Issue 4 , December 2022, Pages 181-185


  SV (sodium valproate) is an antiepileptic drug that is often prescribed for epilepsy, bipolar disorders, and migraine. We reported an SV intoxicated case that cardiac and neurologic abnormalities were promptly responded to hemodialysis (HD). She ingested a large amount of SV (150 pills of SV 200mg) for ...  Read More

Meta- analysis
Antiphospholipid antibodies and COVID-19 mortality and thrombotic events; A systematic review and meta-analysis

Reza Jafarzadeh Esfehani; Mohammad ali khalilifar; Hadi Esmaeili Gouvarchinghaleh; Gholam Hossein Alishiri; Alireza Shahriary

Volume 9, Issue 4 , December 2022, Pages 186-195


  Introduction:Among various proposed pathologic mechanisms during the coronavirus disease 2019 (COVID-19) pandemic, overproduction of autoantibodies is not widely studied. Antiphospholipid antibodies (aPLs) are target proteins that have affinity toward charged phospholipids. APLs are thought to have pro-thrombotic ...  Read More

Original article
Characteristics of pediatric pulmonary hydatid cyst in Mashhad, North East of Iran.

Seyed Javad Sayedi; Hanieh Zandi; Sepideh Bagheri

Volume 9, Issue 4 , December 2022, Pages 196-199


  Hydatid disease is an important health problem in endemic areas like Iran. Unlike adults, the occurrence of pulmonary hydatid cyst is greater than hepatic cysts in pediatric population. In this study we evaluated the characteristics of pediatric pulmonary hydatid cyst in our region. We reviewed ...  Read More

Original article
A comparative analysis of clinical, para-clinical, and laboratory factors in ICU and Non-ICU admitted COVID-19 patients: identifying predictive markers for ICU admission

kamila Hashemzadeh; Ali Esparham; Farnoosh Ebrahimzadeh; Konstantinos Triantafyllias; Zahra Mirfeizi; Maryam Sahebari; Mohammad Hassan J Joker; Mandana Khodashahi; Masoumeh Salari; Bita Abbasi; Delaram Omidvar; Mahtab Ghaemi; Hassan Mehrad-Majd

Volume 9, Issue 4 , December 2022, Pages 200-206


  Introduction: Health care systems all over the world face numerous challenges as a result of the rapid spread of the COVID-19 virus that has resulted in increased mortality rates. About 40% of ICU-admitted COVID-19 patients were not severely ill at the time of admission. Thus, by using appropriate ICU ...  Read More