A New Era of the Fresh Start

Hamid Reza Kianifar

Volume 1, Issue 1 , February 2014, Pages 1-1

  The Journal of Reviews in Clinical Medicine (RCM) is the leading journal of its type at Mashhad University of Medical Sciences covering all aspects of the natural and clinical sciences, which may be a matter of concern for the related specialists. The scope of the journal defines the RCM Publishing ...  Read More

Association of cytogenetics and immunophenotype in prognosis of children with acute lymphoblastic leukemia: Literature Review

Abdollah Banihashem; Ali Ghasemi; Lueisa Tavasolian

Volume 1, Issue 1 , February 2014, Pages 2-6


  Acute lymphoblastic leukemia (ALL) is the most common type of neoplastic disorder diagnosed in childhood. It is the cause of one third of all pediatric malignancies. ALL is characterized by the abnormal production and proliferation of immature lymphoblasts in bone marrow (BM). It seems that ALL occurs ...  Read More

The effect of Tranexamic acid on cardiac surgery bleeding

Mohammad Esmaeelzadeh; Shahram Amini

Volume 1, Issue 1 , February 2014, Pages 7-11


  Serious bleeding in cardiac surgery leads to re-exploration, blood transfusion and increases the risks of mortality and morbidity. Using the lysine analogous of antifibrionlytic agents are the preferred strategy to suppress the need for transfusion procedures and blood products. Although tranexamic acid ...  Read More

How to encounter the child in coma

Mohammad Hassan Aelami; Sepideh Bagheri; Seyed Morteza Rasti Sani

Volume 1, Issue 1 , February 2014, Pages 12-16


  Non-traumatic coma is a medical emergency and should be evaluated as soon as possible. Pediatric coma is more serious because of patient’s capacity of pathological stressor tolerance is limited especially in neonates.Several etiologies could be listed for loss of consciousness (LOC) and coma in ...  Read More

The role of magnetic resonance spectroscopy in differentiation between neoplastic and non-neoplastic focal brain lesions

Sirous Nekooei; Bahareh Haratizadeh

Volume 1, Issue 1 , February 2014, Pages 17-20


  The ability to differentiate between neoplastic and non-neoplastic focal brain lesions is critical for appropriate management of patient. Due to low specificity of magnetic resonance imaging (MRI) adequate data for differentiating would not be provided.Magnetic resonance spectroscopy (MRS) is one of ...  Read More

Serum zinc, copper, selenium, and lead levels in children with chronic renal failure

Forough Rakhshanizadeh; Mohammad Esmaeeli

Volume 1, Issue 1 , February 2014, Pages 21-24


  In the last two centuries, chronic kidney disease (CKD) and renal failure (RF) have been considered as the main medical problems which were fatal in many cases. Trace elements such as selenium, copper, and zinc are the components of biological enzymes which have a crucial role in decreasing reactive ...  Read More

Vasculitic peripheral neuropathy

Mona Amini; Reza Boostani; Maryam Sahebari

Volume 1, Issue 1 , February 2014, Pages 25-28


  Primary systemic vasculitis in pre-capillary arteries is associated with peripheral neuropathy. In some types of systematic vasculitis about 60 % of patients have peripheral nervous system (PNS) involvement. In vasculitic peripheral neuropathies (VPN) a necrotizing and inflammatory process leads to narrowing ...  Read More

Refractory seizures in children

Seyed Ebrahim Mansoorinejad; Farah Ashrafzadeh; Javad Akhondian; Mehran Beiraghi Toosi

Volume 1, Issue 1 , February 2014, Pages 29-32


  Epilepsy is described as a heterogeneous clinical syndrome results from various cerebral destructions. It is categorized to partial and generalized forms. Degree of neural system impairment and affected area determine the severity and pattern of symptoms. Patients might experience sensory, motor, or ...  Read More

The overexpression of COX 2 in Wilms’ tumor

Sara Hashemi

Volume 1, Issue 1 , February 2014, Pages 33-37


  Cyclooxygenase 2 has become an important pharmacological target in anticancer therapy due to the over expression of COX 2 in pathological conditions. Wilms’ tumor is a common kidney cancer in children which has shown an increase in COX 2 enzyme level. Here we reviewed various articles that considered ...  Read More